Meibomian Gland Dysfunction The grading for meibomian gland dysfunction (MGD) showed an increasing trend from Week 0 to Week 4, as evident in Figure 4 .
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The Theil-Sen median trend calculates the median of the slope of n (n − 1)/2 data combinations [ 43 ], and its calculation formula is: (5) S E S V = M e d i a n E S V j − E S V i j − i , 2000 ≤ i < j ≤ 2015 When S ESV > 0, this reflects an increasing trend of the time-series ESVs; otherwise, it reflects a decreasing trend of the time-series ESVs.
The same pattern also emerged for the “decision-making” dimension even though the difference only approaches statistical significance.
Previous studies showed that increasing the upper arm elevation and abduction were related to an increasing trend of discomfort [ 12 , 13 , 14 ].
Despite all efforts to prevent complications from the disease, in recent years there has been an increasing trend in the prevalence of diabetes, mainly type 2 DM (t2DM) non-insulin dependent patients, counting for one of the main causes of mortality in European Union (EU).
an obvious trendgold
Our findings demystify the reported lack of an obvious trend in root caries that was brought to light by Dye et al.
After controlling several characteristics of the children and their families, data from Young Lives sample showed a significant negative effect of poor visual acuity on mathematics tests, marginally significant for vocabulary by analyzing children aging from 7 to 8 in Peru [ 19 ].
Correlations of borderline significance were found between smoking duration and total power, and between daily exposure and HF.
a clear trendgold
In the light of this impact, a clear trend has been observed in the last years towards improving the diagnosis process for that type of diseases, aiming not only to reduce detection time but also to optimize the patient’s care and treatment, while at the same time reducing as much as possible the negative effects on their health that come mainly from late diagnosis and inappropriate treatments [ 1 ].
In this regard, some authors have suggested that r > 5 is practically significant [ 62 ].
Study Limitations and Further Considerations The OXCGRT stringency index is a ‘low resolution’ composite measure that does not account for nuances in sub-national government responses, which may be significant where state-level measures vary widely between jurisdictions (e.g., in the USA).
In addition, the bivariate associations show highly significant results (0.1% significance level) between the demographic variables (marital status, gender and ethnicity), socioeconomic status (education, employment status), mental health (depression, stress and anxiety), all diagnosed chronic diseases except urinary tract and kidney diseases and the three income groups, B40, M40 and T20 ( Table 2 ).
Immigrants represent over one fifth (21.9%) of the Canadian population, which is an increasing trend [ 6 ].
Previous studies that approached SmO 2 using other NIRS positioned in the vastus lateralis during a dynamic maximum knee extension exercise obtained results that were very similar to those obtained in this study, revealing that the knee extension exercise caused a slight increase in this variable and then a decreasing trend according to all the publications consulted [ 19 , 35 , 36 , 37 ].
Several of the significant determinants of CIM in the European sample of this study are also significant in Hong Kong, e.g., distance to school, age, neighborhood settlement types (in our sample: street connectivity, accessibility of public transportation, and availability of open spaces), and density are significant in both Europe and Hong Kong, but household income is significant in Hong Kong but only marginally significant in Europe.
The prevalence of cyberbullying perpetration, victimization, and their overlap varies in different countries and research contexts, and there has been an increasing trend in recent years [ 10 ].
an overall trendgold
Compared to normative PSS-10 data, our means showed an overall trend of higher averages in the country-level analyses we report (e.g., Germany and Mexico; we were unable to find pre-pandemic PSS-10 data for Pakistan) [ 12 , 47 , 52 , 53 ].
Other studies suggest that there is an increasing trend in gambling, the prevalence growing rapidly in adolescents to decline in young adulthood [ 69 , 85 ].
In a study aimed at determining the prognostic factors of perceived health 3 months after surgery, the use of walking aids before the fracture was evidenced as a significant and independent risk factor for a low PCS-12 score, PCS-12 score prefracture, and cognitive dysfunction, while the only statistically significant and independent risk factor for a low MCS-12 score was the prefracture MCS-12 score, and while the female gender demonstrated marginal significance [ 46 ].
a negative trendgold
For males and according to LOWESS, we found a steady trend from the youngest ages to middle adulthood (around age 55), following a negative trend until the age of 74 and an increase from there.
This result was also confirmed by regression analysis: geographical location entered in the model with a p -value at the limit of significance).
As the significance test for small coefficients that are of no practical significance tends to be statistically significant in a large sample [ 24 ], we chose the absolute value of correlation coefficient > 0.3 [ 25 ] as the threshold of being practically significant in this study.
According to Figure 4 , the early-warning value of ecological security in the Qinghai alpine agricultural mountainous area showed an increasing trend each year.
In recent years there has been an increasing trend in exploring the extent of SB in older people, especially in the community.
All the aforementioned studies have shown that ryegrass as high-quality pasture vegetation has highly significant effects on the environment, however, the wide application of QN antibiotics in domestic livestock industry will also have adverse effects on ryegrass.