Bodyweight A three-way ANOVA evaluating change in bodyweight from 4 months (time of irradiation) to 11 months (beginning of behavior tests) of age revealed an unexpected highly significant main effect of radiation exposure ( p = 0.01) and an expected significant effect of sex ( p = 0.04) ( Figure 1 C).
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At 48 h, the 30 and 60 μM groups had a highly significant lower viability compared with the control ( p < 0.01).
Notably, the two adjacent codons (259 and 261) exhibit very strong purifying selection, with near-zero dN:dS and highly significant p -values ( p ≤ 0.01).
One and two symbols above the histogram represents a significant difference ( p -value < 0.05) and an extremely significant difference ( p -value < 0.01).
At 2 h post-infection, the virulence of the deletion strain ∆ preA in EPC cells was 1.3-fold higher than that of the parent strain; the difference between the two strains was extremely significant ( p < 0.01). 2.6.
The mRNA expression level of Sp5-HTR1 in the gills showed highly significant downregulation ( p < 0.01) at 4 and 12 h ( Figure 4 D).
Statistically, “**” indicates highly significant differences ( p < 0.01), “*” indicates significant differences ( p < 0.05), and “N.S.” indicates non-significant differences ( p > 0.05). 5.
Phenotypic Evaluation The analysis of variance for each treatment revealed highly significant differences ( P < 0.01) in all 24 studied traits between the 96 genotypes (data not shown).
Likewise, a highly significant positive correlations existed between expression of CD40 and expression of P53 and P65 (r = 0.201, P < 0.01, r = 0.277, P < 0.01, respectively).
The difference analysis results showed that the difference between the two different concentration groups was extremely highly significant ( p < 0.01) ( Figure S1 in File S1 ). 2.2.
Correlations were considered significant at p < 0.05 and highly significant at p < 0.01.
In both L-CSL groups, the mRNA levels of Nrf2 and Nqo1 were significantly higher than those in the SHR group ( p ≤ 0.01), with a highly significant difference between the two CSL doses ( p ≤ 0.01).
A series of highly significant correlations (r s = 1.000, p < 0.01) were identified among Otx2 protein levels across multiple ocular tissues, including the lens, optic nerve, ciliary body, iris, sclera, and eyelid.
Additionally, Muribaculum exhibited a highly significant negative correlation with ileal IL-17A ( p < 0.01) and a significant negative correlation with hippocampal RORγt ( p < 0.05).
Serum TMAO showed a highly significant positive correlation with colonic NLRP3, IL-18, and TNF-α ( p < 0.01) and a significant positive correlation with kidney NLRP3 and IL-1β ( p < 0.05).
EXTP promoted root elongation ( Figure 2 I), which was highly significant ( p < 0.01) compared with both CK and DS.
All six time points show p -values below 0.05, with most comparisons demonstrating highly significant differences ( p < 0.01, Figure 3 B).
Concurrently, an increasing trend in the frequency of Foxp3 + Tregs was observed ( p < 0.01); however, given the limited sample size ( n = 5), this finding should be interpreted with caution and requires further validation in larger cohorts.
Postoperative anti-glaucoma medications showed a highly significant intergroup difference ( p = 0.01), being most frequent in RRD (56.9%), followed by dropped IOL/lens (50.0%).
In the hepatopancreas ( Figure 5 B), both Mn-HexA1 and Mn-HexA2 displayed a highly significant increase in expression from stage He1 (hepatopancreas in O1 stage) to He2 (hepatopancreas in O2 stage) ( p < 0.01), reaching peak levels at He2 stage that were substantially higher than all other developmental stages ( p < 0.01).
Statistical significance followed conventional threshold criteria; differences between experimental groups were considered statistically significant when p < 0.05 (*), representing a 95% confidence level in the observed difference, and highly significant when p < 0.01 (**), corresponding to a 99% confidence level.
In particular, the relative abundance of Pseudoalteromonas showed a highly significant correlation with water temperature ( p < 0.01, ρ = 0.835).
A single asterisk indicates significant differences (0.01 < P value < 0.05) and a double asterisk indicates extremely significant differences ( P value < 0.01).
During sibutramine therapy, expression of miR-378 in SAT tended to increase but did not reach statistical significance, while in plasma, a reliable increase in the miR-378 level was revealed ( p = 0.01) ( Figure 1 C,D).
Compared with the control group, the body weight and average food intake of mice in each model group increased significantly ( p < 0.05), with highly significant increases in average food intake at 3 weeks, and body weight at 9 and 12 weeks ( p < 0.01). 2.3.