Excerpts

The evening cortisol levels in the 2 Gy group decreased from 275.5 ± 39.4 to 217.5 ± 33.2 ng/mL ( p = 0.05) with borderline significance ( Figure 3 b).

CHD mortality rates have increased in American women within the age range of 35–54 years, contrary to a decreasing trend in the past four decades from 1980 to 2000 [ 2 , 4 , 5 ].

showed that in addition to a better functional class, successful PVL closure was demonstrated to reduce cardiovascular mortality (OR = 0.08, CI95% 0.01–0.90), with a positive trend in the overall mortality, and it also reduces haemolytic anaemia (OR = 9.95, CI95% 2.10–66.73) [ 30 ].

Our study evidenced that serum IL-6—as an important promoter of inflammation—levels determined on the day of admission showed an increasing trend through higher IS tertiles.

The overall analysis, though characterized by substantial statistical heterogeneity (I 2 65%, p < 0.01), confirmed a tendency towards significance for the association between respiratory symptoms and female sex (OR 1.20, 95% CI 1.00–1.45).

Thus, the DMFS survival curves of the two groups showed the same trend as in OS, whereas the p -value was 0.052, which was marginally statistically significant, possibly due to the small sample size.

The increase in the CFR for the entire year was significant in the case of CHF (adjusted OR-adjOR 1.226 95% CI: 1.172–1.282) and borderline significant in the case of non-STEMI (adjOR 1.104 95% CI: 1.001–1.217), but was not significant in the case of STEMI (adjOR 1.091 95%CI: 0.934–1.275), although this varied from period to period.

Bellner et al., 2004, found that there is a highly significant correlation between ICP and PI, regardless of specific intracranial lesions [ 22 ].

Nevertheless, the LBM as well as BCM and ECM/BCM Index changed after surgery with a significant reduction of LBM and BCM between t1 and t2 and an almost significant reduction when comparing t2 to t4.

Specifically on non-contrast computed tomography (CT), there may be significant overlap between heterogeneous shape, density, and various non-contrast markers of ICH expansion [ 4 ].

The increase in the cancellation rate showed a decreasing trend with time, despite the COVID-19 pandemic.

No statistically significant differences were observed in the control arm or for the rest of the anthropometric parameters, but a positive trend was observed in the intervention arm for the triceps fold.

The injury severity factor entered in the previous block now showed a barely statistically significant effect.

Although not statistically significant, these pooled results showed a trend of higher complications observed in the M flap group.

The pulp short T2 component showed a trend toward statistical significance.

All of the individual statins examined showed a trend of a reduced risk of variable magnitude without differences regarding lipophilicity, while moderate and high intensity of treatment seems to present a greater effect.

Association of Statins with CRC by Active Principle, Lipophilicity and Intensity By active principle, we found a trend of a reduced risk with the current use of all statins, albeit statistically significant results were only reached with simvastatin (AOR = 0.86; 95% CI: 0.80–0.93) and rosuvastatin (AOR = 0.58; 95% CI: 0.41–0.83), being marginally significant for atorvastatin (AOR = 0.92; 95% CI: 0.84–1.00; Table 3 ).

However, despite the reduced number of patients, the analysis suggested a clear trend towards a greater PFS and OS in the pro-immunogenic group, as might be expected.

Interestingly, PSBM9 was not selected under our criteria but almost reached statistical significance in our study (FDR = 0.01 and log 2 Fold Change = 0.96, upregulated in the pro-immunogenic subgroup) which suggests that our biomarker filtering criteria could perhaps be reassessed in order to identify additional genes with potential as biomarkers.

Tumors defined as pro-tumorigenic showed a trend to accumulate certain molecular aberrations and were found in a higher proportion of relapsed patients.

Nevertheless, COP patients showed a trend toward fewer permanent ECG changes after TAVR supporting the previously seen decrease in conduction disturbances.

Even though from a biological perspective, activating mutations would be expected to have similar effects irrespective of the specific mutation, the KRAS models at most only showed a trend for the totality of KRAS mutations in predicting a reduced risk of a PFS event, remaining non-significant overall.

Higher age and the use of BEAM conditioning substantially increased the risk of hospitalization, but were not quite significant variables.

A significant trend of decreasing ORs for intermediate AMD associated with increasing Varied staple food diet scores was noted ( p for trend = 0.002).

Meta-analysis of family involvement/participation almost reached significance level and explained 14% of the variance.