Excerpts

The height and width of subretinal hyperreflective material were statistically greater in patients presenting during the pandemic, while the height and width of subretinal fluid approached significance as well.

Research on melanoma has shown how PFS and OS showed either a strong trend or significantly better outcomes as TMB (tumour mutational burden) increased when treated with immunotherapy [ 25 ]. 6.

Interestingly, there was a very early numerical increase in ischaemic events in patients without aspirin, because of a nonsignificant trend toward increased risk of MI (HR 1.26, 95% CI 0.72–2.16) and ST (HR 1.32, 0.46–3.79) ( Table 1 ). 4.

TAT increased 60%, with a number needed to harm of 274 and an associated borderline significant increase of MI.

Although in our study the 2.3 increased odds were just barely not statistically significant, combined with recent literature we believe an additional risk-point should be awarded indicating higher risk of a fast, more aggressive disease progression or failure of therapy [ 37 ]. 5.

However, the CTG showed a trend toward improvement at T2, with a similar magnitude of improvement (6 points) to that of T3 (5.36 points), where a significant reduction was indeed observed.

Although, in general, there is a major improvement between the age of 1 and 2 years, with only a minority still having feeding problems after the age of 2 years, as long as the feeding problems continue, the impact on the quality of life of both NS infants and their caregivers may be significant.

CRC patients showed a trend for decreased Gln levels compared to controls, but levels were similar as in AA patients.

Interestingly, serum PTH levels showed an increasing trend over time and its serum levels increased compared to baseline at all the time points assessed in the Patient group.

Bellner et al., 2004, found that there is a highly significant correlation between ICP and PI, regardless of specific intracranial lesions [ 22 ].

Higher age and the use of BEAM conditioning substantially increased the risk of hospitalization, but were not quite significant variables.

A significant trend of decreasing ORs for intermediate AMD associated with increasing Varied staple food diet scores was noted ( p for trend = 0.002).

An analysis of 17 NSCLC patients treated with nivolumab showed a trend of a more prolonged OS in those with high INF-γ expression compared with those with low INF-γ expression [ 94 ].

A p -value of <0.05 was defined as significant, a value of <0.01 as highly significant and a value of <0.001 as very highly significant.

This is similar to a previous study that reported non-significant or weakly significant correlations between clinical parameters [ 18 ], with correlation coefficients of <0.2.

The ordinary multivariable logistic regression models in this cohort demonstrated that the association between each factor and extubation outcome was plausible as an overall trend. 4.3.

The favorable outcomes group showed a slight trend towards increase in blood ammonia levels as prehospital time increased, while a stronger correlation was noted in the poor outcomes group; blood ammonia levels were markedly increased as a result of prolonged prehospital time.

Confluent mass-forming or infiltrative liver metastasis patterns were associated with liver metastasis at initial recurrence or metastasis but with borderline significance.

Some other inflammatory biomarkers, such as CRP ≥ 16.5 mg/L [ 98 ], ESR ≥ 32.5 IU/L [ 99 ] and 35 α-hydroxybutyrate dehydrogenase (HBDH) ≥ 259.5 IU/L [ 99 ] also have indicative significance for RMPP in children.

A significant decrease in the steroid dose was confirmed up to 12 months after irrigation; after 12 months, there was a decreasing trend, albeit without statistical significance ( Table 3 ). 3.3.

A two-sided p value of <0.05 was considered statistically significant and ≥0.05 but ≤0.1 was considered a trend towards significance.

found a highly significant reduction of IH after OR when a mesh was implanted compared to conventional fascia closure.

The patients from higher Mallampati grades had a higher need for active oxygen therapy, with a clear trend to introduce NIV in these patients, while Mallampati IV was identified as an independent predictor of active oxygen therapy in our analysis.

Digoxin use has been largely relegated to advanced heart failure and refractory atrial fibrillation, as initial trials showed a trend toward increased mortality in these populations [ 137 ].

The difference in central density was marginally significant, with a p -value of 0.049 (6.78 ± 4.74 mm −1 vs. 8.44 ± 4.33 mm −1 ).