Excerpts

Despite these challenges, there was a positive trend in family mental well-being, with scores increasing from 5.1 in 2020 to 6.7 in 2022 ( p = 0.031).

The result for SNP rs1063320 in human leukocyte antigen G ( HLA-G ) gene did not reach statistical significance after correcting for multiple testing (uncorrected one-sided p-value, p = 0.031; FDR-corrected one-sided p-value, p = 0.198) ( Table 2 ).

FT4 concentration decreased gradually from the no calcification group to the mixed calcification group ( p = 0.000); TSH concentration showed an increasing trend ( p = 0.032) ( Table 3 ).

However, the Mann–Whitney U test comparing the biceps brachii group and the brachialis plus brachioradialis group on pronator teres toxin dose showed a trend towards significance ( p = 0.033, adjusted alpha = 0.0167), suggesting that patients in the biceps brachii group tended to receive a higher dose of pronator teres toxin.

A marginally significant time-dependent effect was observed for LDL-C ( p = 0.033 and p = 0.032, respectively); however, given the non-significant global test and the absence of meaningful effect modification, this single covariate deviation at the conventional threshold is unlikely to materially influence the robustness of our primary conclusions ( Supplementary Table S11 ).

Pre-gestational DM showed a nominally significant inverse association (OR 0.32; 95% CI 0.11–0.91; p = 0.033); however, this result should be interpreted with caution given the very small number of pre-gestational DM cases ( n = 22 total).

Moreover, a significant trend towards increased in-hospital mortality was found in propensity score-adjusted regression in the unmatched population (odds ratio 3.12, p = 0.035), but this result was not significant in the matched cohort ( p = 0.095). 4.

There was an increasing trend in the use of early CAG over the years ( p = 0.037 for trend). 3.2.

The Jonckheere–Terpstra test showed a trend toward decreasing OT with calendar year on the left side ( p = 0.037) (surgeon’s non-dominant side), but not on the right ( p = 0.795).

The results of the Jonckheere–Terpstra test showed a significant trend in decreasing operative time with calendar year for surgeries on the left side ( p = 0.037) ( Figure 2 A) but not the right side ( p = 0.795) ( Figure 2 B).

Additionally, blood transfusions were more frequent in the middle-aged group than in the older group, with a strong tendency toward significance (15% vs. 4%; p = 0.038).

Among diabetic patients, a nominally significant difference in unadjusted event rates was observed (12% vs. 35%, p = 0.038), though this exploratory subgroup analysis requires cautious interpretation given the small sample and absence of adjustment for confounders. 4.1.

Contrastingly, for rs2268493 of the OXTR gene, individuals with the minor allele exhibited lower SW (B = −0.145, p = 0.012) and Lp (B = −1.912, p = 0.010) but showed a trend toward higher GE (B = 0.011, p = 0.038) and LE (B = 0.018, p = 0.042).

Neonatal birth weight was numerically lower in the ICP group; however, after BMI adjustment, this difference did not reach statistical significance (unadjusted p = 0.039; BMI-adjusted p = 0.064).

Women showed a marginally significant better survival when analyzed using the log-rank test ( p = 0.04).

The on-treatment HBeAg seroconversion in these patients showed a trend toward significance, with 71.4% (5 out of 7) in the MASLD-CHB group compared to 44.9% (40 out of 89) in the CHB non-MASLD group ( p = 0.04).

When these parameters were analyzed based on the status of the disease ( Table 4 ), only lysine and BCAAs (valine and isoleucine) continued being lower in patients with active disease; however, only valine had a positive trend test (JT-TT) (b-Tau 0.30, p = 0.04).

There were highly significant differences concerning 7- ( p = 0.04) and 30-day mortality ( p = 0.002).

Results: The benefit of colchicine in reducing MACE risk was marginally significant (RR = 0.79, 95% CI: 0.63–0.99, p = 0.04, I 2 = 59%).

Conversely, robust direct correlations were found with urinary sodium excretion (R = 0.700; p < 0.0001), LVMi (R = 0.543; p = 0.0007) and age (R = 0.418; p = 0.007) ( Figure 2 ), while a barely significant correlation was found with gender (Rho = 0.319; p = 0.04).

4; p = 0.02; OR 0.04; CI95% 0.31–0.94), and showed a trend towards older age (42 vs. 30 years; p = 0.04; OR 0.16; CI95% 0.99–1.06).

Statistical analyses of the differences between the AUC demonstrated that the incremental improvement in correct classifications achieved with the IV plus clinical variables model (as compared with clinical variables alone) was of borderline significance ( p = 0.04). 4.

The test for overall heterogeneity was highly significant (Q(4) = 10.14, p = 0.04), reflecting the notable variability in the results.

Finally, the number of symptoms at diagnosis was a marginally significant predictor of the number of symptoms three months after recovery ( p = 0.04).

In the multivariate data meta-analysis (fixed effects), there was a borderline significant association between sarcopenia and OS (fixed effects, HR = 1.20, 95% CI: 1.01, 1.44, P = 0.04, I 2 = 43%; k = 5; n = 831).