Barely Significant

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In the free acidity ( Figure 10 A) and acetyl content data ( Figure 10 B), a clear trend can be observed: in the sample stored without any inhibitors, the deacetylation process was dramatically pushed until a lowering of the overall degree of substitution of the polymer (from cellulose diacetate to cellulose monoacetate [ 3 , 31 ]); a similar trend was also evident for RMPF stored in the presence of pure PVF and WP, for which the deacetylation was only slowed down.
When the Ni doping amount was greater than 0.1, the polarization impedance showed an increasing trend again because with the continuous increase in the doping amount, the excessively high oxygen vacancy concentration caused defects in the cathode material and led to the localization of oxygen vacancies [ 21 ], thereby reducing the O ion transport rate and increasing R p .
Taking the partial significance descriptors discussed above as an example, we suggest adjusting the large ring counts to decrease the molecule’s hydrophobic surface area and optimize ring connectivity in order to control the number of five-membered aromatic rings to decrease the potential for reactive metabolite formation and reduce the likelihood of generating toxic intermediates.