Excerpts

In this study, CoronaVac® showed a trend to protect against hospitalization and severe cases, though without statistical significance.

It reveals an increasing trend of lattice strain attributed to the microstructural evolution following In doping and prolonged sintering time, consistent with TEM observations and GPA analysis.

Effectively, a negative trend in internal stress is a positive trend for ice-ocean stress, as it implies a more direct transfer of atmospheric momentum to the ocean.

The largest trend in surface stress occurs during winter (5.1% per decade), while fall also exhibits a significant trend (2.1% per decade), although this curve flattens after 2060.

The peak area exhibited an increasing trend as the concentration of defects increased from D-AAS-12 to D-AAS-25 (Supplementary Fig. 10a, d, g ).

The surface area showed a decreasing trend from 525 ± 25 m 2 g −1 in AAS to 485 ± 18 m 2 g −1 in D-AAS-12 and further to 473 ± 24 m 2 g −1 in D-AAS-25 (Fig. 1g–i ).

C3 staining showed a trend for an increase upon PMX205 treatment correlating the RNA-seq data (Supplementary Fig. 11 ).

A robust linear regression analysis yielded a highly significant correlation between pseudovirus neutralization test (PNT) and MNT log2 values (Fig. 3a, b ), with a coefficient of determination ( R 2) exceeding 0.95 for both strains, underscoring a high degree of methodological agreement.

GHG emissions GHG emissions from future hydrogen production industries might be significant and are likely 0.7–0.9 GtCO 2 -eq. year −1 in ambitious climate scenarios, which inevitably require carbon dioxide removal practices to compensate for these residual emissions to reach net-zero goals 29 .

The collected viral load showed a decreasing trend over time since symptom onset (Supplementary Fig. 17 ), which was observed in other literature 23 , 49 , 50 .

Results of the cognitive screening test MoCA stayed in the normal range for patient 2, whereas patient 1 showed a trend of decrease in the MoCA score and developed a mild cognitive impairment during the study.

Along with the developmental path from CD8_C8_CXCL13 to CD8_C11_HAVCR2 cells, we observed an increasing trend for exhaustion scores but a decreasing trend for stem-like scores (Fig. 7d , Supplementary Fig. 13c , and Supplementary Data 4 ).

28 , which examined these parameters in batch cultures with different carbon sources, reported an increasing trend in r and B with the bacterial growth rate, along with a non-monotonic trend in τ .

6B, D ), and highly significant statistical differences between active MASTER-NAADP and inactive MASTER-NADP for the number of peaks (Fig. 6C ), and the mean responsiveness (Fig. 6D ).

Overall, mean DOC concentration in China’s lakes increased from 14.79 ± 12.49 mg L −1 in 1984 to 18.14 ± 21.75 mg L −1 in 2023, with an increasing trend in 65.4% of lake area.

Although this enhancement in vitro is not as dramatic as expected, it might be significant in vivo because the actual concentration of Mst7 and Pmk1 in vivo might be much lower than that used in the in vitro assay.

We note that despite the highly significant muscle eQTL, VGLL3 was lowly expressed in human skeletal muscle (median transcripts per million (TPM): muscle = 0.9 TPM), whereas it was highly expressed in human adipose tissues (subcutaneous adipose: 24.8 TPM, visceral adipose: 17.4 TPM, GTEx 60 : Supplementary Data 8 ).

With regard to heating, the market for heat pump (HP) systems in Europe shows an increasing trend with record high installations of over 2 Mio. in 2021 16 .

For the cumulative sea ice production (SIP) in June to August of each year during 2000–2013 available from satellite estimates, there was an overall trend of increasing SIP with increasing winter SAM (Fig. 3a–n ).

The presence of an excess of highly significant P -values for cells harboring targeting gRNAs versus non-targeting controls (NTCs) also indicates that this multiplex framework successfully detects upregulation of genes from CRISPRa perturbations (Fig. 2d ).

We next performed a within-trio analysis, quantifying the difference in PGS liability between a proband and each of their parents and compared this quantity with repeated random sampling from nominally significant PGS with matching direction of effect and not linked to proband VUS HPOs (N permutations = 10,000; median PGS per proband = 168).

There was also a strong trend for the DEGs to have only one or two exons.

Expressions of core autophagy genes 27 showed a trend of decrease with age at both the mRNA and protein level in the liver (Supplementary Fig. 9 ), a tissue in which age-related decline in autophagy activity has been well demonstrated 28 , 29 .

Lungs of the NS8593 treated mice showed a trend towards less immune infiltration, correlating with the decreased illness exhibited by NS8593 treated mice (Fig. 8f ).

Specifically, in humans, we observed a dominant occurrence of C-mode 1 and 2 (Kruskal–Wallis test, p < 0.001) while mice occurrence of sensory-oriented C-mode 3 and 4 was observed instead (Kruskal–Wallis test, p < 0.001), with macaques showing equiprobable (Kruskal–Wallis test, p = 0.25) C-mode occurrence (although a slight trend for a mouse-like profile was apparent).