Barely Significant

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The chromosome specific aneuploidy was further analyzed by quantitative FISH ( Figure 3B–E ), which revealed an induction of: 1) trisomy 21 and 12 by OX-LDL and a borderline significant induction of trisomy 21 and 12 by LDL ( Figure 3B and D ), and 2) induction of tetrasomy 21 and 12 by both OX-LDL and/or LDL ( Figure 3C and E ).