Barely Significant

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Conversely, in the Breast Cancer International Research Group (BCIRG)-001 trial the combination of docetaxel (Taxotere®), doxorubicin (Adriamycin®) and cyclophosphamide (TAC) offered a significant improvement in 3-year DFS in patients with luminal B (defined as ER-positive, PgR-positive and either Ki67 high or HER-positive), but only a marginal trend in patients with TNBC or HER2-enriched tumors over treatment with fluorouracil, doxorubicin, cyclophosphamide (FAC).
highly significantqualifiedgold
DNA Fragment Size Matching Facilitated by the FSM Method is More Critical to Array Quality than Previously Identified Factors Having demonstrated the highly significant contributions of FSM analysis and matched DNA fragment sizes to aCGH quality, we sought to further assess the relative effects of fragment size compared to other previously reported variables such as Proteinase K digestion time, array hybridization time, and concentration and source of DNA in array hybridization reactions.