Excerpts

This is a highly significant increase over previous levels ( t = 14.79, df = 94, P<10 −5 ).

Inter-rater reliability was highly significant (Cohen's κ = 0.62; Z = 19.1; P << 0.00001; number of errors = 90).

The difference in the concordance of these 2 data sets was highly significant (p<0.00001).

During the Conditioning phase, highly significant (p<0.00001) main group and training day effects were observed and those were sustained over the entire period of Conditioning.

The subjects’ own educational attainment showed a nominally significant negative association with F roh ( p = .045), while the contribution of parental education to offspring F roh was highly significant (father: p < 10 -5 ; mother: p = 9×10 -5 ), with more educated parents having offspring with fewer ROHs.

The increments in luciferase activity produced by the addition of increasing amounts of human rMCP-1 to antigen stimulated cells were significant for the allele 1G (ANOVA F = 10.23, p = 0.005) and highly significant for the allele 2G (ANOVA F = 172.3, p <0.00001).

For example, witnessing violence toward siblings on the MACE showed a highly significant association with DES scores (β = 2.02, t = 4.75 p < 10 -5 ), whereas witnessing interparental violence did not (β = 0.60, t = 1.44, p = 0.15) and experiencing physical abuse had only a marginal association (β = 0.85, t = 1.83, p < 0.07).

The overall effect was highly significant (Z = 7.70, p < 0.00001), further supporting the effectiveness of this dosage.

All pair-wise comparisons showed highly significant levels of population genetic differentiation (P<10 -5 , Table S2 ).

In particular, the differences are highly significant on branch #1 and branch #2 during the genome reduction period (Student's t-test, P- value<10 −5 ).

Only highly significant meta-analysis results (p-values <0.00001) were used to select a subset of SNPs – AD-associated genes confirmed by numerous studies [17] .

Group differences were highly significant at the overall p = 0.00001 level.

Combining data from neuropathological and clinical replication cohorts revealed highly significant associations of all ten GAB2 variants (9.7×10 −11 <p<1.2×10 −5 ) with LOAD.

A highly significant protective effect for HLA-A*02 : 01 was observed in females (OR = 0.63, p = 1.21 x 10 −05 ), while no effect was seen in males ( Table 4 ).

The reduced model 2 without the ‘taxon’ term gave a much worse fit to the data, resulting in a highly significant likelihood ratio test (χ 2 = 19.12, 1 df, p -value = 1.228 x 10 −05 ).

This first set of results was obtained with high levels of reproducibility, obtaining highly significant values when the data concerning treatments with R8-PNA-a221 and R8-PNA-a221-MUT are compared (p <0.0000123 in five independent determinations.

Two further general population cohorts, KORAF4 and SAPHIR confirmed the association, and a meta-analysis of all three cohorts (11,258 individuals) was highly significant (p = 1.3x10 -5 , OR = 7.46).

A case/control series in hepatitis C related disease demonstrated highly significant detection (p<1.72*10 −5 ) of patients at high risk of developing HCC.

This is a highly significant enrichment (p-value = 1.98e-5, hypergeometric test).

ID 653 was therefore experimentally regrouped into the viral group, which resulted in a highly significant p-value ( p = 2e -5 ; Fig 7B and 7D ). 3.2.2 Bacterial No statistically significant group differences could be detected for bacterial presence in this investigation.

The difference between the cumulative growth in the number of PVCs in the control and riluzole groups was highly significant, at p<0.00002.

A role for cis -regulatory elements in methylation fidelity was also demonstrated by highly significant (p<2.2×10 −5 ) enrichment of transcription factor binding sites in CGI probe loci showing heritably high (118 elements) and low (47 elements) methylation, and also in loci demonstrating stochastic hyper-(30 elements) and hypo-(31 elements) methylation.

We employed standard ANOVA F-tests [ 59 ] to evaluate the significance of the interaction term (reflecting varying slope by treatment group) and found that the evidence did not support inclusion of the interaction term (P = 0.93) when comparing these two models, but when comparing the simpler model to the trivial model that ignores treatment group (adjusted R 2 = 0.75), the ANOVA F-test P-value is highly significant (P = 2.3e -5 ), supporting the inclusion of group-specific intercepts, but not group-specific slopes, in the final model.

For CS- tones, a highly significant increase in SSA occurred after conditioning ( Fig 4F , 16%, F(1,1801) = 18, P = 2.3*10 −5 ).

In contrast, a higher minor allele frequency (15.6%) of the p.Leu1007fsX1008 (rs2066847) frameshift mutation was seen in patients with aggressive disease, compared to 8.2% in patients with mild disease which was highly significant (p = 2.63x10 -5 , Table 2 ).