Excerpts

In a univariate logistic regression, we observed a highly significant positive association between the composite index score and the likelihood of aflatoxin detection (OR 1.6, p < 0.0001).

The Q test for heterogeneity was highly significant between studies (p<0.0001), and the I 2 statistic was 99%, indicating high heterogeneity.

There was a constant, highly significant difference in time to retinopathy over the entire range (for 140/80 mmHg 22.4 vs 24.7 years, logrank test, chi square 44.91; p<0.0001), suggesting the absence of any threshold below which retinopathy is being prevented.

The resulting linear regression equation, optimized for Amemiya Prediction Criterion, is highly significant (correlation coefficient = 0.787, r - 2 = 0.606 , P<0.0001, α = 0.05, see Fig 14 ).

Both the treatment and center effects for k 1 were highly significant ( p <0.0001).

Since 30 tropical forest locales lacked elephants carrying S-clade mtDNA, while S clade was detected in 34 of 51 non-tropical-forest samples, the association was found to be extremely significant (Fisher's exact test, two-tailed p <10 −4 ).

The profiles of IgG in urine in the curative treatment group showed a significant trend of decline with time post-treatment (Kruskal-Wallis test = 113.4–212.6, p value < 0.0001) and the lowest levels were seen 12 months post-treatment.

2 ), the mean number of circulating CD20 + B cells in the 3 treated animals (0.04±0.2 B cells/μl blood) was 1000 fold lower compared to untreated animals (393±70 B cells/μl blood) and this difference was highly significant (p<0.0001, unpaired one tail T test).

The AMOVA analysis showed that although the most of the genetic diversity was attributable to differences among individuals within populations (85.78%), the φ ST values among populations were highly significant ( φ ST = 0.141 p< 0.0001) confirming the existence of population differentiation.

A clear trend was apparent, as each concentration of C . pallidum caused a marked significant increase ( p < 0.0001 for all) in mineralisation level.

For SCO the total number of patches (average of 24.6 patches +/- 0.770) was found to be highly significant increased (p < 0.0001) compared to NSP (17.7 +/- 0.465), ( Fig 4A ).

Lower PlGF MoM and higher MAP MoM were also found in LO-PE pregnancies, however the difference in PlGF MoM did not reach statistical significance (MAP –1.05 MoM, p<0.0001; PlGF –0.90, p = 0.024).

The preference for reachable locations was highly significant ( χ 2 test, two nearest LEDs against the three farthest ones, P<0.0001).

The model outputted a distribution of values with highly significant difference in their means (p < .0001) ( Fig 5 ).

On the other hand, the group of subjects who received PI vaccination showed a trend toward an increase in the median IgG titer (median values of 0.3 to 579 (P<0.0001), 0.00–401.4 (P = 0.3125), and 971.3 to 2163 (P = 0.3008) in group 1,2, and 3 respectively), except slight decrease of IgG value for Group 4 (median value of 1067 to 1021; P = 0.9717).

When all observations of Xe effects on freezing at PR-LTM1 were pooled from these two independent experiments (Air-exposure, n = 20; Xe-exposure, n = 21) there was a highly significant reduction in freezing both to context alone ( t 39 = 4.63, P<0.0001) and context + tone ( t 39 = 2.16, P<0.01) compared to air-exposed controls.

The mixed linear model analysis using the SAS procedure PROC MIXED revealed highly significant differences among the genotypes and genotype × environment interactions for SEV and IT ( P <0.0001).

ANOVA revealed a highly significant main effect of condition. with maximum in the lower gamma range at 30–45 Hz (p<0.0001, Fig. 3 ).

Two-way ANOVA analyses proved that the cortisol treatments affect male and female cell responses differently; the interaction was considered extremely significant (interaction p value < 0.0001; F = 392.7; DFn = 2).

A highly significant stimulatory effect on the number of buds per polyp was observed under increasing feeding regimes in both species ( A . coerulea : F (2, 168) = 223.21, P<0.0001; A . relicta : F (1, 158) = 130.39, P<0.0001; Table 2 ).

An increasing trend was observed for overall TDR when comparing 2000–2005 (6.0%) and 2006–2015 (8.2%) (p<0.0001), which was associated with significant NNRTI TDR increase (p<0.0001).

= 21.5) was highly significant with t(116) = 5.5, p < 0.0001.

However, there was a highly significant intra-subject correlation between pre- and post-treatment irisin concentrations (R = 0.82, P<0.0001).

The correlation between log 10 building mortalities (m) and log 10 population size (N) was highly significant ( r = 0.57, P <0.0001, n = 147), as was the correlation between log 10 tower mortalities and log 10 population size ( r = 0.43, P <0.0001, n = 188) ( Figure 1 ).

Importantly we observed highly significant treatment effects, independent of time-point, between control and treated (500 IU/mL IFN-γ) samples for all three KP enzymes: IDO-1 p<0.0001, KMO p = 0.0023 and QPRT p = 0.0002 (Fig B in S1 File ).