Excerpts

There was a highly significant correlation (p = 0.0004) between M. tuberculosis presence in the larvae and the absence of treatment ( Figure S2 ).

The masculinization approached significance (p-value = 4E-4) in 5 wk old Trim24-null mice vs. wild-type mice from the same study ( GSE19675 ).

Adrenalectomized male mice 6 hr after injection with another GR agonist (dexamethasone) (1 mg/kg) approached significance for feminization (p-value = 4E-4) ( GSE24256 ).

2–6 d old (= pooled 2–3 d old and 4–6 d old nestlings) and 7–9 d old nestlings, still showed highly significant differences between these two groups of nestlings (MANOVA, in each case P ≤ 0.0004; for Age, df = 3 and 87.0; and for Brood identity(Age), df = 3 and 256.04).

This proportional difference was highly significant (p = 0.0004).

Factors explaining seropositivity in animals In cattle, age had a highly significant effect on animal seropositivity (P-value = 0.0004), indicating that the older the animal, the more likely it is to become infected and hence be seropositive.

Kaplan-Meier analysis revealed a highly significant difference in MFS between the two classes ( P = 0.0004).

This increase was highly significant ( p = 0.0004, Fisher's exact test) ( Table 1 ).

The interaction effect between diabetes and FBG was highly significant (p = 0.0004), and we therefore performed separate analyses for patients with a diagnosis of diabetes and for those without.

For generosity we found highly significant correlations with total T (r = −0.25, two-tailed t test, N = 200 for this and subsequent tests, p = 0.0004), free T (r = −0.1908, p = 0.0068), and DHT (r = −0.3063, p = 0.0001); see Fig. 4A .

In comparison, only 4 of 19 (21%) CD14-KO mice developed symptoms of ECM indicating that loss of CD14 confers a highly significant protection from ECM (p<0.0004, Fisher's exact test).

A meta-analysis in 2002, which used data from 18 trials and 2074 patients, indicated a highly significant reduction in the risk of death with NACT (HR 0.65, 95% CI 0.53–0.80, P = 0.0004) [ 14 ].

In the jejunum, both buprenorphine and tramadol caused a highly significant decrease in MPO activity in comparison with chemotherapy-treated control animals (53%, p = 0.0004 and 58%, p = 0.0001 respectively, Fig 2A ).

AD pathology also had a large and highly significant relation with hippocampal volume (−0.38 cm 3 , P = 4.1×10 −4 ).

Intersection of the top 5% of each of the two rankings yielded highly significant overlaps, with 37 overlapping genes for SARS (p-value∼2e-6, genes in table 4 ) and 24 for influenza (p-value = 0.00043, genes in table 5 ).

The difference between the glucose levels in the STZ-induced and normal mice was highly significant ( P = 4.34E-04).

Two SNPs located in genes that were implicated by previous GWA studies of ALS were marginally significant in the pooled analysis of discovery and replication samples: rs17174381 in DPP6 (p = 4.4×10 −4 ) and rs6985069 near ELP3 (p = 4.8×10 −4 ).

These correlations, although weak (r– 0.17, r– 0.14 and r– 0.24, respectively), were highly significant (p = 0.0005, p = 0.005 and p<0.0001, respectively), ( Table 3 ).

However, the abandonment rates of den-captured bears were highly significant even when comparing with overall abandonment rates (χ 2 (1, N = 76) = 20.5, p<.0005) or when excluding those occasions where bears moved dens early in the season (χ 2 (1, N = 56) = 45.2, p<.0005).

Observable differences are highly significant; performing one-sided Mann-Whitney U tests (with the alternative hypothesis c treated > c untreated ) leads to the rejection of the null-hypothesis (p < 5 x 10 −4 ) for all metabolites.

The differences between the L p values at 0°C and those at 10°C were highly significant (p<0.0005).

Further ANCOVAs exploring the effects of group and hemisphere for each tract showed a highly significant effect of group for the UF, F(1,23) = 20.03, P<0.0005, and no corresponding effect for the IFOF, F(1,23) = 0.16, P>0.6.

The Welch’s ANOVA assessment found that the difference in mean FBS between the groups was highly significant ( P = 0.0005 ) ( Table 1 ).

Changes of ESAS were highly significant, as well as the use of opioids and breakthrough pain medications (p <0.0005).

Correspondingly, a highly significant difference for MFI comparing rosetting cultures of blood group A and partly rosetting of blood group O was seen for PAvarO (p = 0,0005) that disappeared with the growth with the pgIgG that prevents rosettes to form in culture (p = 0,0686).