Excerpts

First, we saw a highly significant reduction of C. tyrobutyricum in microfiltration trial (PT1) compared to PT2 and PT3 (average abundance ratio: 4768x more abundant in PT2 and 4721x in PT3 than PT1.

In fact, mouse models represent a highly significant experimental approach, allowing for the investigation of site-specific, cellular, and molecular responses that cannot be directly studied in humans [ 16 , 17 ].

With the increase of ABSI, the overall PFI showed a decreasing trend.

Our 141-hypothesis screen demonstrated that the same geometric feature can appear highly significant under feature-shuffle controls but completely non-significant under rewiring controls or strict max-null auditing.

An ANOVA of the relationship between the variance of the evidence and deliberative length on the one hand, and epistemic success on the other, indicates that both of the former parameters are highly significant (F = 2027 and 18, respectively), though the relative importance of variance is much greater than deliberative length.

For malignant neoplasms, a decreasing trend persisted even after the pandemic’s start across all groups.

Overall, a declining trend was noted in all-cause mortality regardless of sex and marital status; however, an increasing trend emerged after the pandemic started.

RMSSD showed a trend to be decreased between the surgery start and end, and to recover afterwards ( Fig 2B ).

Child program results Child participants (n = 85) reported highly significant positive changes in all measured outcomes when compared from initial admission to graduation from the program (see Table 2 ).

Evaluation of the age dimension revealed no significant statistical differences between groups (Q = 1.28, p = 0.53), yet the effect sizes exhibited a decreasing trend with advancing age ( Fig 3B ).

From a health economics perspective, this finding is highly significant: it implies that the payer-classification structure of the Iranian insurance system — specifically, the distinction between domestic IRR-denominated and preferential currency-denominated claims — is a stronger predictor of hospitalization duration than most clinical or demographic attributes.

Despite a reduction in the total number of dispensed items and a decreasing trend from 2019−2023, costs are seen to rise in the most recent year for which data is available ( Fig 3 ).

Over the decade, there has been a clear trend of increasing WASH coverage across almost all regions, with the national average rising from 22.13% in 2011 to 50.17% in 2022.

Expansion: Qualitative data explains or nuances a statistical trend (e.g., high quantitative well-being scores contrasted by qualitative insights showing mothers suppress pain to prioritize childcare).

In terms of the changing patterns of HF burden, most Asian countries show an increasing trend.

A-P differencing analysis revealed highly significant differences between inflammation and healthy controls.

Therefore, the observed near-significant association between smoking and LFHL in the multivariable model was expected.

The finding that all ChatGPT-5 responses received a JAMA score of 0 suggests a notable trend in how free-tier LLMs provide information.

For the standard deviations, “V+ Xia ” is significantly more dispersed than “V+ Xiaqu ” (p = 0.0016, one‐tailed), but the difference between “V+ Xia ” and “V+ Xialai ” shows a marginal trend and does not reach statistical significance (p = 0.065, one‐tailed).

The earlier ≈7-fold increase at ≈43–36 kya is suggestive but not significant, although the increase is significant when compared over a much longer time period, e.g. from ≈25 kya to the coalescent.

Furthermore, a significant trend towards higher ORs with decreasing PLT/WBC ratio was observed across the tertiles ( P for trend = 0.002).

A large positive value of S indicates an increasing trend, whereas a large negative value indicates a decreasing trend.

The authors compare a variety of drought indices in this highly significant region.

However, the rate of increase gradually diminishes, reflecting a clear trend of diminishing marginal benefits.

The significance levels were determined according to the following criteria: an F-value greater than F0.01(2,2) indicated a highly significant effect (***), an F-value between F0.05(2,2) and F0.01(2,2) indicated a moderately significant effect (**), and an F-value between F0.1(2,2) and F0.05(2,2) indicated a generally significant effect (*).