Barely Significant

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40 had found no and hardly significant effects in some scales (e.g. the EBI) in Germany; in the Swiss interactive group webinar trial these effects could not be detected at all, although the population of the trials and the culture are quite similar: In an online setting, emotions and the impact of role plays are potentially buffered: people cannot move around, approach or leave each other; group dynamics and empathy with fellow group members are less intense than in real groups who meet in person for six weeks and experience a certain feeling of group coherence 47 .
Furthermore, pathway enrichment analysis indicated that alterations in amino acid metabolism, fatty acid metabolism, and Pan and CoA biosynthesis were associated with the development of DR 38 ; moreover, aspartate, glutamine, and Pan were the key factors related to the differential enrichment of these pathways, and Pan level in the vitreous cavity showed an increasing trend.