The relative amino acid composition of FFS and LFS varied in accordance with DoF and the relationship was found to be highly significant (ANOVA, p < 0.00001).
Excerpts
Furthermore, a robust association between observed and predicted responses for TC degradation was evident from the highly significant regression model (p-value < 0.00001), high coefficient of determination (R2 = 0.9886), and well-adjusted R2 value (0.9780) 18 , 59 .
All hallmarks showed highly significant differences (adjusted p < 10e-6), indicating robust biological distinctions.
The F-ratio comparing the variances across time was highly significant (F 479,479 = 14.5144, P < 0.00001).
Although both effect sizes of PM 2.5 and PM 10 in the fully adjusted models were small (β-value of PM 2.5 = − 0.032; β-value of PM 10 = − 0.039, respectively), they were highly significant ( P -value < 0.00001).
In our study, the 2R/3R genotype was the most prevalent among Jordanian women, representing 69% of the control group and 50% of breast cancer patients—a difference that was highly significant ( p < 0.00001).
The chi-squared goodness of fit test showed that 46.5% (1115) of the markers significantly differed from the expected 1:1 Francis to Rondo allele ratio at p < 0.05 and 7.6% (182) of the markers had highly significant segregation distortion at p < 1e−05.
However, since there are only around 80 confirmed and 120 predicted imprinted loci in total in the human genome, the observation of even just ten of these genes in our study represents a highly significant enrichment ( P < 1 × 10 −5 ; permutation test).
The paired Wilcoxon test showed highly significant (p < 0.00001) Δ T core ( t ) differences between the time-dependent core temperatures T core ( t ) of the following barrel pairs: artificial zebra versus grey horse, artificial zebra vs. grey cattle and artificial zebra vs. real zebra.
Although Pd-MOF produced a highly significant downregulation of VEGFR2 gene expression in A549 cells compared with the untreated control ( p < 0.00001; Fig. 7 D), its inhibitory potency remained considerably weaker than that of the reference drug, sorafenib.
Finally, infected C57BL/6 mice displayed a highly significant decrease in the abundance of Gastranaerophilales (Fold change = −17.96, p = 0.00001; DESeq. 2) (Fig. 6b ).
For this process we filtered our complete data set by 1-way ANOVA to enrich for mass features with highly significant information ( P < 10 −5 ) in regard to the distinction of seed classes either excluding or including the colour variants of each seed type (Table S2 ; columns AV-AW).
Statistical result interpretation The one-way ANOVA test revealed a highly significant difference in AgNPs size among the four extract concentrations (F = 98.48, p < 0.00001), indicating that nanoparticle size is strongly influenced by extract concentration.
The next 2 genes (low density lipoprotein receptor ( LDLR ) and tissue inhibitor of metalloproteinases metallopeptidase inhibitor 1 ( TIMP1 ) showed moderately significant upregulation (p < 1 × 10 −5 ) in gene expression between D20+ TGF-β and D20 samples, as detected by RNASeq analysis and a significant upregulation at D20+ TGF-β vs D20 by real-time PCR (Fig. 4H,I ).
This difference is statistically highly significant (p < 0.00001, χ 2 -test, confidence interval: p < 0.05).
The results were highly significant for all parameters (Wald χ 2 (1) < 10,000, p < 0.00001 in all cases).
Enrichment for liver-relevant gene sets To provide an easily interpretable enrichment statistic, for liver-relevant pharmacogenetically important gene sets, we used logistic regression to provide natural log odds ratios at the gene level for gene set membership and the presence/absence of a nominally significant cis -eQTL or eGene ( p < 10 –5 ).
This difference between TLE subtypes was highly significant (p < 10 −5 , randomization test).
All correlation coefficients between these two datasets were above 0.99 (Pearson’s r ) and highly significant with p < 1e-5.
Genome-wide significance was the accepted P < 5 × 10 −8 while marginal significance was P < 1 × 10 −5 .
Association study Supplemental Figure s1 illustrates a highly significant correlation ( P = 0.001%) between grain filling rate and heat susceptibility index with grain yield.
In fact, highly significant ( P < 10 −5 ), down-regulated DEGs were more abundant than up-regulated ones (blue circles in Figures S3 , S4 , and S11 ).
The dF/S analysis revealed a highly significant enhancement of syx-GFP cluster formation of over 60% by vSyx (p < 0.00001, Fig. 2D ).
Prep1 DR induced a 2-fold increase of highly significant DNA-binding sites (p < 10 −5 ) in P versus C cells before differentiation at day −2, and a further 2-fold increase 4 hours after induction of differentiation (Fig. 4B and Supplementary Fig.
An rmANOVA comparing WJ-Fluency to both WJ-Basic Reading and WJ-Comprehension showed both a highly significant main effect of group ( F (1,55) = 12.8, p < 0.00001) and a highly significant group X test interaction ( F (2,54) = 5.64, p = 0.006), with significant differential deficits of Fluency vs. both Basic Reading ( F (1,55) = 8.43, p = 0.005) and Comprehension ( F (1,55) = 10.9, p = 0.002).