Excerpts

Although individual comparisons at the level of individual gene loci failed to reach statistical significance (Fisher test, p > 0.05 for each gene locus), a marginally significant improvement in overall knock-in efficiency was seen when considering all the gene loci together (Chi squared, p = 0.046, Supplementary Table 6 ), although the large variability in efficiency caused by gene locus complicates this analysis approach (see below for a more rigorous approach).

Diet is found to have no statistical effect on neutral head posture (p-value = 0.516), and its relationship to the reconstructed cranial orientation is barely significant (p-value = 0.046).

There was a marginally significant effect of noise on maximum distance (i.e., gesture size), χ 2 (2) = 6.16, p = 0.046.

Interestingly, we observed that frequencies of CD4 + CD28 null T cells showed a moderate correlation with both maximum CRP values after surgery (r = 0.214; p = 0.020) and a marginally significant correlation with the total leucocyte count after surgery (r = 0.185; p = 0.046) (Table 2 ).

However, when using the AFO, there was a borderline significant increase in clearance (p = 0.046).

Though at the limit of significance (p = 0.046), deep deletion of SIRT6 tends to co-occur with PIK3CA amplification/activating mutations (Fig.

was recorded in only one sample of SNOW and five samples of ICE, with a p-value at the limit of significance ( P = 0.046), indicating that this result has to be interpreted with caution (Fig. 5 a and b and Table S6).

Histopathological analysis Histopathological analysis revealed marginally significant differences across groups in duodenal inflammation severity (KW H = 5.833, p = 0.046) and colonic inflammation type (H = 5.333, p = 0.041).

A previous meta-analysis that evaluated restrictive transfusions ranging from 7 to 10 g/dL found that such treatment significantly reduced in-hospital mortality, though the effect on infection was only marginally significant (p = 0.046) 10 .

Kruskal–Wallis test showed a slightly significant difference between treatments ( H = 7.990, df = 3, P = 0.0462).

Overall, a total of thirty-one SNPs were nominally significant (2.34 × 10 −4 < p < 4.66 × 10 −2 ) in this single SNP analysis.

Additionally, patients with stage III-IV showed slightly higher METTL1 expression than those with stage I-II, with the difference being marginally significant ( p = 0.047) (Fig. 2 D).

There was a marginally significant effect of test period (χ 2 1 = 3.94, P = 0.047; Fig. 2b ).

The age-standardized mortality rate for cancer in the six provinces in northwest China was stable overall from 2013 to 2021 but exhibited a decreasing trend from 2017 to 2021 (APC = − 5.64%, p = 0.047), male cancer age-standardized mortality rates were consistently higher than those of women and plateaued, women exhibited a decreasing trend after 2017 (APC = − 5.56%, p = 0.032), and the standardized mortality rate was higher and stable for those aged ≥ 65 years.

45.2%) with borderline significance (adjusted RD = 26.01, p = 0.047), whereas no difference was seen in nondiabetics (Table 4 ; Fig. 3 a and b).

Another important finding was that male (615.6 ± 311.50 pg/ml) and female (701.5 ± 267.50 pg/ml) GAD patients showed no significant variation in serum IL-23 levels (p = 0.385, two-tailed student t-test). Association between different demographic and clinical covariates with GAD severity The correlation between IL-17A and GAD-7 scores was found to be statistically significant (r = 0.397, p = 0.032), with the correlation being most pronounced among females (r = 0.578, p = 0.048) and approaching significance among males (r = 0.459, p = 0.047) (Fig. 1 bi).

There was also a marginally significant positive correlation between ECI2 and EZH2 mRNA expression (F = 4.15, p = 0.047, Fig. 3 F).We observed a positive correlation between the mRNA expression and protein expression for each marker in the PC group.

The difference between bacterial communities from the two canyons was weaker (R = 0.254) than the difference between the two species, and the difference was barely significant (p = 0.047).

However, subject age was marginally significant, with younger subjects reporting higher maximum pain (P = 0.047).

The slopes for women were significant or approached significance in the theta, p =.047, and gamma, p =.05, bands but not the alpha band ( p =.84).

Although only marginally significant in Chinese (rs7088318, OR = 1.23, P = 0.047), the PIP4K2A association also showed consistency across populations.

There was also a significant effect of signal-to-noise ratio (F(8,56) = 4.359, p = 0.001, ƞ 2 = 0.384) and a marginally significant interaction between the two factors (F(8,56) = 2.139, p = 0.047, ƞ 2 = 0.234).

Instead, for the hemagglutination titre, we found a marginally significant positive association with body mass index, albeit effect sizes were small (estimate = 0.003, SE = 0.002, N df=1,172 = 179, χ 2 = 3.94, P = 0.047, Fig. 3 ); indicating higher hemagglutination levels for nestlings in better condition.

Removal of the 14 potential outliers resulted in a pooled SMD of 0.410 (95% CI 0.005–0.815) which was only marginally statistically significant ( t = 2.08, P = 0.047).

Total allometry (calculated as a linear regression of Procrustes coordinates onto log transformed centroid size (CS)) in the RV species-averages dataset was significant (p = 0.0011) and accounted for almost 14% of total variability; while the evolutionary allometry (calculated as a regression of independent contrasts of shape onto independent contrasts of log transformed CS) was around 10% and was barely significant (p = 0.047).