Excerpts

A Permanova analysis confirms that there were highly significant differences in the multivariate CHC profiles across the different treatment groups ( F = 37.76, p < 0.0001).

There is a highly significant difference (p < 0.0001) in the antimicrobial effect between the prepared PVA:SA:TiO 2 nanocomposite films and the positive control group.

The repeatability of measurements between observers was highly significant (R = 0.914, CI = 0.866, 0.945, p < 0.0001) and the variation in gametocyte densities within each extremity of each individual represented only 0.01% of the variance.

Moreover, when plastic particles used in toxicity testing were classified into 4 size classes, the effect of particle size on toxicity was highly significant (ANOVA, p < 0.0001), and the dependence of safe concentration (HC 5 ) on particle size was even more remarkable, with a slope b = 1.21 according to the equation: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\log \;{\text{HC}}_{5} = 1.21\;\log \;{\text{S}}{-}2.10$$\end{document} log HC 5 = 1.21 log S - 2.10 where S is the mean particle size (μm) for each size class (r 2 = 0.92, n = 4).

In total, about a two-fold increase in seeds was observed in reduced tillage plots (7936 seeds m −2 ) compared to ploughing (3846 seeds m −2 ) in the 0–20 cm topsoil layer, which was highly significant (ANOVA, F-value 24.5, p < 0.0001).

The main effects of stimulus intensity, recording site, and their interactions were all highly significant, F4,152 = 96.29, p < 0.0001, η 2 = 0.82; F2,76 = 68.75, p < 0.0001, η 2 = 0.73; and F8,304 = 5.06, p < 0.0001, η 2 = 0.72.

In rats (n = 4), four out of five studies with one study reported on VLDL level instead of LDL level, reveal a highly significant reduction in LDL (SMD = − 4.847, p < 0.0001) and CI for this effect ranges from − 5.693 to − 4.002.

All 135 features exhibited highly significant between-class differences ( p < 0.0001), with the majority showing p-values very low.

One-way ANOVA demonstrated a highly significant effect of incubation time on biofilm formation ( p < 0.0001, R 2 = 0.966).

As shown in Table 1 , the analysis of variance (ANOVA) of the response surface quadratic model indicated that the regression model obtained was highly significant (P < 0.0001) with an F value of 263.99.

ventralis with Y2 were highly significant ( p < 0.0001) (Fig. 4 ), and A . wilkella was recorded exclusively in the samples of this subcluster.

At higher concentrations (12.5–50 μg/mL), the extract exhibited pronounced inhibitory activity, with highly significant reductions in biofilm biomass compared to the control group (*** p < 0.0001).

The model, as well as the parameters in the model, were extremely significant (P < 0.0001).

9 Analysis of Variance (ANOVA) results for the model showed it to be highly significant overall (F = 427.62, p < 0.0001) (Table 3 ).

Kaplan–Meier ‘survival analysis’ applied to freedom-from-tumors, followed by a stratified log-rank test for equality of survivor function showed a highly significant difference between the Keap1 flox/flox /Nrf2 +/+ and Keap1 flox/flox /Nrf2 −/− groups (χ 2 = 14.5; p < 0.0001).

We found a highly significant correlation for the oligomers generated from both HypF-N (r = 0.93, P < 0.0001) and Aβ 42 (r = 0.95, P < 0.0001).

Significance values are denoted by asterisks as defined by GraphPad Prism version 6.04: ****extremely significant (p < 0.0001); ***extremely significant (0.001 ≤ p ≤ 0.0001); **very significant (0.01 ≤ p ≤ 0.001); *significant (0.05 ≤ p ≤ 0.01).

Consequently, the Group × Task × Trait interaction remained highly significant (β = 0.89, SE = 0.19, Z = 4.59, p < 0.0001).

The scraper inclination angle (X2) exhibited a highly significant main effect (F = 518.11, p < 0.0001), and its quadratic term (X22) was also highly significant (F = 833.74, p < 0.0001), demonstrating that scraper inclination had a pronounced influence on the application rate.

Among them, G exhibited an extremely significant effect on the angle of repose ( p < 0.0001), whereas F and J showed significant effects ( p = 0.0279 and 0.0155, respectively).

Although there was no significant residual difference in the CNV size (p = 0.18) or numbers (p = 0.11) between the mGluR+ and mGluR− groups, there was a highly significant difference in the presence of syndromic features between the mGluR+ and mGluR− groups (p < 0.0001).

Principal Curve scores show a positive relationship with chlorophyll a (representing the biomass of primary producers) ( edf = 2.8, P value < 0.0001) but negative with fucoxanthin, which is a proxy of diatoms, dinoflagellates, and chrysophytes ( edf = 4.03, P value < 0.0001), whereas in another model, the scores and alloxanthin, which is a proxy of cryptophytes, display a positive trend ( efd = 3.63, P value < 0.0001; Fig. 6 ).

An independent samples t- test was performed which showed a highly significant difference difference in the crowding effect between the older and younger group ( t(30.92)= – 5.83, p < 0.0001, Cohen’s d=-1.94) [see Fig. 8] .

Furthermore in the hanging wire grip test requiring strength and coordination the FE65/FE65L1-DKO mice had a significantly lower latency to fall compared to WT mice, while single KOs, which also showed a trend towards a lower latency to fall, were not significantly different from WT mice ( Fig. 1c , p = 0.0001).

A highly significant positive correlation between YP and HI traits (r: 98% at a P < 10 −4 ) based on estimated Pearson’s correlation coefficient (r) was observed.