Barely Significant

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showed a trendp = 0.1282.6× alpha
Notably, transplanted patients who received RQ-PCR MRD-negative autografts, regardless of whether obtained after the first or the second R-HD-ARA-C course, showed a trend towards PFS advantage, even if not statistically significant (median PFS 56 and 37 months for negative and positive LK MRD samples respectively, p = 0.128) (Fig. 4 ).
showed a trendp = 0.1312.6× alpha
Although non-significant (NS), patients with incongruent results (one low/one high, n = 10) showed a trend of having a favorable prognosis compared to patients with high results from both modalities (log-rank p = 0.131), but inferior compared to patients with low uPAR-estimates on both modalities (p = 0.136).
marginally insignificantp = 0.142.8× alphagold
For graft failure, hypercholesterolemia was significantly associated with increased risk in recipients without mTOR therapy (HR 1.85, 95% CI 1.17–2.90, p = 0.01), while it showed a marginally insignificant association with decreased risk of graft failure in recipients with mTOR therapy (HR 0.49, 95% CI 0.19–1.26, p = 0.14), and the interaction had a p -value = 0.01.