Barely Significant

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highly significantqualifiedgold
A SWISS-MODEL analysis revealed that the class A carbapenemase KPC-2 in the database has a three-dimensional (3D) structure matching that of PAD-1(GQME value 0.67, QMEAN value −1.61), which is highly significant in carbapenem resistance, especially in clinical Enterobacteriaceae isolates 11 .
2 - are selected for further investigation. 12 out of the total 16 steroids that show Bonferroni significance appear in two sub-networks, the first with 8 Bonferroni significant steroids, and other 2 nominally significant steroids, and other 2 unknowns: X-12844 and X-11440 (interestingly these are tentatively identified by Metabolon as tetrahydrocortisone glucuronide and hydroxypregnen-diol disulfate (or pregnenolone-diol disulfate) respectively), and the second sub-network with 4 steroids and one unknown.