Excerpts

However, an increasing trend for lung cancer and breast cancer was observed during four periods.

showed a decreasing trend in ages at spermarche and menarche in four- or five-year intervals during 1991–2014 based on small sample size 20 .

These changes showed an overall trend from more acquisitive and less drought- and heat-tolerant strategies in low-light conditions and in MIX, to more conservative and drought-tolerant strategies in high-light conditions and in OAK.

No sex differences were observed for changes in time spent in Work , Education , Sedentary Leisure , or Other (all p > 0.1). Large and highly significant twenty-year decreases were also detected for PAL and AEE (Table 2 ; Supplementary Table S2 ).

1 shows, mean annual temperatures in the study area ranged from 10.45 °C to 14.02 °C, with an average temperature of 12.2 °C, and there was an increasing trend of 0.039 °C per year during the study period.

Data from the TCGA for breast cancer accessed through Oncomine showed a trend toward lower expression of PISD in invasive ductal carcinoma relative to normal breast tissue, although extensive overlap exists (Supplementary Fig.

The evenness showed a decreasing trend between the start and end of the experiment, and the difference was significant ( P < 0.005) in communities with high initial evenness.

Therefore, there is an increasing trend in feed industry to develop lipases as feed additives.

Eleven candidate miRNAs (shown in Supplementary Table 1 ) that were particularly abundant and for which the difference in expression in serum was highly significant were selected to determine the validity of the previously obtained results.

Nevertheless, the comparison of the different CH variants showed a trend of general better binding measurements when using the human IgG Fc capture AHC biosensors (Fig. 5 ) over that of Protein L biosensors (Fig. 3 ).

Although, we noticed an increasing trend in expression of FAS in OCILy3, it was not significantly different under hypoxia.

Initial data analysis of SUDHL2 dataset failed to detect GLUT1 and HK2 because of the highly significant pre-established criteria set for RNA enrichment co-correlation analysis.

Functional analysis of the differentially expressed mRNAs In evaluating the top differentially expressed mRNAs (n = 250), we found a highly significant enrichment for several functional annotations (Supplemental Fig. 5 ), including acetylation (genes post-translationally modified by the attachment of at least one acetyl group; n = 85 genes; Fold enrichment = 2.2; Bonferroni-adjusted p = 4.2 × 10 −11 ), mitochondrion (the site of tissue respiration

In the multivariable-adjusted model, those in quartile 3 had lower odds of severe DR or worse versus the combined no DR and minimal-moderate DR categories, than those in quartile 1 (OR, 0.35; 95% CI: 0.17 to 0.74; P = 0.006; per categorical increase in severity Model 2 in Table 2 ), and a significant trend for increasing frequency of fish consumption (P-trend = 0.024).

The maximum loading rates under different preset pressure are listed in Table 1 , where an increasing trend can be observed.

We also found that CHBs belonging to haplogroup D5 showed a trend towards having a very high VL and a lower frequency of VL <100 IU/mL (Fig. 3 ), which was considered as the cut-off for clinical HBV-DNA negativity.

The statistical significance of phenotype variables was assessed with the function anova.cca in vegan package, using 999 permutations to test for the marginal significance of each term after accounting for the effects of the others.

The SAH volume showed a trend to be a negative determinant (OR, 0.91; CI, 0.81 to 1.01) for favorable outcome.

P < 0.05 was considered statistically significant and P < 0.10 was considered to be trending toward significance.

There was no significant change in the intensity or area of the B-form helix conformation of DNA, while there were quite significant changes for the Z conformation of DNA.

Due to the fact that the P value was close to significance threshold, we performed additional separate paired Student’s t -tests (uncorrected), to test whether differences between both conditions (EF vs IF) occurred for any phase.

Both of the top peach and shrimp allergy associated SNPs were nominally significant in apple and crab reactive subjects (Top peach SNP: rs28359884, P apple = 5.75 × 10 −6 ; Top shrimp SNP: rs74995702, P crab = 1.22 × 10 −3 ).

For the taxa that differed between HC and NAFLD, partial correlations between diagnosis status and abundance were highly significant after controlling for BMI or IR.

Additional pathways that showed a trend towards enrichment involved processes related to cell growth, proliferation, and apoptosis and included cell epidermal growth factor receptor (EGFR) signaling and the PI3 kinase and p53 pathways (p = 0.07–0.09).

We also observed an interesting trend that microhomology was less commonly associated with deletions of ≥50 bp (Table 2 ).