Excerpts

Among the 20 OMIM derived gene-lists (CNS+ above 19), for the 78 sb-RPD gene set, statistically significant overrepresentation at p < 0.0025 (0.05/20) was noted for gene lists annotated with clinical synopsis terms ‘central nervous system’ (p cor = 0.026), ‘head and neck’ (p cor = 0.037), and a nominally significant overrepresentation for ‘peripheral nervous system (0.057) (Supplement S2 and S3 and Supplementary Table 4 ).

Negative temperature trends for summer from 1958 to 1990 and a positive trend from 1991 to 2001 were found for the Baltoro glacier in the Karakoram using the ERA-40 reanalysis dataset 18 .

They concluded that (i) the daily temperature range is consistently widening for all seasons, (ii) mean and maximum temperatures of winter show significant increases and (iii) mean and minimum summer temperatures show a decreasing trend.

The comparison of NBI percentage among the subgroups within group II showed no significant difference, with a decreasing trend over time starting at 2 weeks post-extraction (Table 8 ).

The comparison of NBI percentage among the subgroups within group I showed significant differences ( p < 0.05), with an increasing trend over time starting at 4 weeks post-extraction (Table 8 ).

NKA showed a decreasing trend with the increase in temperature, and a U-shaped trend with the increase in salinity.

However, a slightly non-significant tendency of a decreased richness and diversity in naive patients compared to the controls was observed, along with a partial recovery after INSTIs-based treatments.

However, the p-values achieved from Cox regression analyses were less than 0.001 for age, sex, and their interaction; and there was a clear trend that the degree of BMI and childbirth correlate with the risk of idiopathic MH.

Weekly temporal evolution of ∆Ct NR over the study period evidenced three significant changes: a decreasing trend in ∆Ct NR was observed between weeks 20 and 30, ∆Ct NR then increased during weeks 37–41 and finally decreased again after week 49.

As can be observed in the pH range from 2 to 5, the RLS signal at the maximum had the intensity of ~ 200 a.u., which evidenced fairly significant aggregation effects.

They achieved a significant trend of decrease in access-related infection rates.

When whale length was found to be a significant predictor of occurrence, we also used one-way ANOVAs with polynomial contrasts to test for a significant trend in the length of whales at increasing IE.

According to the variance analysis results of each item in the regression equation (Table 2 ), F value of Model was 54.65, P value was < 0.0001, indicating that Model was extremely significant.

Notably, the first main peaks of absorption appear at the energies of 5.00 eV, 5.75, 6.25 eV for the BC 2 N, BC 2 P and BC 2 As monolayers respectively, while all monolayers show almost insignificant absorption properties in the low energy region of the electromagnetic spectrum.

One hundred fifty-three of 1027 metabolites assayed were significantly different based on disease status and 474 metabolites were nominally significant (Supplementary Table S1 ).

25 and 26 , the maximum value of the surface settlement decreases with an increase in the tunnel’s burial depth, and the surface settlement on both sides of the tunnel shows an increasing trend, indicating that the influence range of the surface settlement increases, i.e., the width of the surface settlement trough increases.

The surface settlement shows a decreasing trend with an increase in the thrust of the shield machine and an improvement in the grouting quality.

Similar findings were also observed in Phase 2 study, where in Group 3, the mean PSS score was 15.9 ± 2.5 for Group A and 21.6 ± 6.2 for Group B, and the difference was highly significant with a p value of ˂ 0.0001.

The results showed a decreasing trend in the serum PRL level in the samples collected after 30 min (Group 2) and 60 min (Group 3), in contrast to the samples collected at 0 h (Group 1).

Notably, however, treatment of SV-HUC cells with BCEVs resulted in extremely significant increases in the release of monocyte chemotactic protein 1 (MCP-1), and this upregulation was even more pronounced when these urothelial cells were treated with CSE- or MEL-induced BCEVs (Fig. 2 C).

An increasing trend of temperature from 298 to 358 K during the adsorption process revealed negative amounts of ΔH and ΔG, indicating the spontaneous and exothermic nature of the process.

In the CTRL run, the late-winter ML temperature shows a decadal variation and a positive trend (0.038 °C year –1 ) in the STMW formation region (Fig. 7 c).

The precipitation across the IRB showed a decreasing trend under MRI-ESM-2.0.

These studies clearly show that the ratio, temperature modifies the DPPH activity positively in the middle region and then follows a negative trend for longer extraction times.

By the additive model, the G allele was associated with a lower HBsAg seroclearance rate with a borderline significance in genotype B infection.