Excerpts

An overall trend of increasing toxicity severity along with dose is observed, but this has high patient-to-patient variability for a given dose range.

S4 , in all subjects, the proportion of fasting CDCA showed a trend of decrease in I-IFG (18%), CGI (16%) and T2DM (13%) compared with NGT (31%).

Lu and Fan 25 showed that average potential yield showed an increasing trend from north to south in most of the NCP by using the EPIC (Environment Policy Integrated Climate) model.

Nevertheless, nine of them (rs541503 ( PHGDH ), rs715 ( CPS1 ), rs272893 ( SLC22A4 / OCTH1 ), rs9393903 ( ELOVL2 ), rs3204953 ( REV3L ), rs603424 ( SCD ), rs174550 ( FADS1 ), rs499974 ( MOGAT2 ), rs7157785 ( SGPP1 )) showed nominally significant association with diabetes in published data from bigger GWAS consortia for type 2 diabetes (up to 110.452 individuals) or exome array analyses (up to 75.670 individuals) of which two (rs174550 ( FADS1 ) and rs3204953 ( REV3L )) were significant after correction for multiple testing by FDR (Table 3 ).

Such a meta-analysis identified fifteen consistently coexpressed PPI modules associated with chronological age, including a highly significant module enriched for ‘T-cell activation’.

In contrast, landings showed a decreasing trend in the Adriatic Sea.

When data from these two sub-areas were combined, there was also an increasing trend in landings of salema over time.

However, even though most of the 55 isolates showed a trend towards plant growth enhancement, the five strains examined in detail excel at plant growth promotion.

The power of significant and marginally significant results was estimated using the pwr . r . test function in the pwr package in R with alpha set to 0.05.

As the number of trips increases, the average entropy of passengers who share the same number of trips first increases, then has a decreasing trend in general, and finally loses its trend when the number of trips increases so much that the sample size becomes too small.

The spatial entropy varies within a considerable range at each value of the number of visited stops n , although the average entropies regarding each specific number of visited stops exhibit an increasing trend.

The rain was marginally significant, but with a very weak negative effect.

When normalized by soil C, cumulative C efflux showed a trend of convergence among the treatments with different residue addition rates (Fig. 1d ).

S6 ) and DCUK-OEt can produce highly significant potentiation of α1β3γ2 and α1β3δ-mediated currents at the EC 10 concentration of GABA in our assays, and probably at concentrations of GABA consistent with those encountered in locations outside of the GABA synapse.

p66shc deletion caused an almost significant reduction in running performance, indicating that p66shc-dependent ROS production is instrumental for muscle recovery upon damage (Fig. 3B ).

P < 0.05 indicates significant difference, while P < 0.01 refers to extremely significant difference.

Although not reaching the statistical significance, the analysis of granzyme expression showed a trend of increase of Granzyme B positive Vδ2 T-cells in ZIKV patients compared to HD (KW = 0.07, Fig. 4d ).

Decreased lipid digestion cannot be completely ruled out in HFD-fed Timp4 −/− mice as these mice showed a strong trend in decreased pancreatic lipase activity compared to HFD-fed WT mice.

Interaction between C18:0 and APOE on HOMA-IR and insulin approached significance.

Abstract The prevalence of asthma and allergic diseases is disproportionately distributed among different populations, with an increasing trend observed in Western countries.

The GAMM for Nephrops condition (expressed as the weight of a standardized length individual) over the trawling gradient in the Irish Sea was marginally non-significant (Fig. 4C , Table 1 ).

There was extremely significant correlation between diversity index and TOC and AN.

Although RhoA showed a trend towards increased activity following Gc exposure, this was not statistically significant (p value 0.9 at both 3 hour time point and 24 hour time point).

As reported previously in Whitehall, we showed a clear trend of lower sugar intake with higher BMI in men 60 .

By systematically employing our software’s ability to detect and visualize subtle, yet highly significant, regional differences in the fluorescent trace of a muscle-specific mitochondrial marker, we have established a protocol for the discovery of subtle variants in mitochondrial morphology.