As shown in Table 2 , the NC versus dementia (female) comparison with the 5 peak–based test shows a highly significant difference ( p value = 0.002), which remains below the Bonferroni‐corrected threshold (α = 0.006).
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Only one of these patients developed oral mucositis, a difference that was highly significant (P = 0.002).
Survival according to site of initial distant metastasis Nuimber Site of of patients first distant I-- metastasis MI F Soft tissues 33 45 Visceral or osseous 62 52 Cerebral 11 13 Total 106 110 Median survival (months) M F 6 8 3-5 7 4 3 4 7 p N.S. 0 002> N.S. 0-02 No treatment Surgery Radiotherapy Chemo- or immunotherapy Combined modalities Unknown M 33 4 21 14 26 8 F 31 5 21 18 28 7 Total 106 110 aries, disparity between the sexes was highly significant (P = 0 002).
In three cases (5.1%), more than one sample was available from the same tumour and in these cases, Ki-67 index varied by no more than 8%. Correlation of Ki-67 index with known prognostic factors Ki-67 index was correlated with known prognostic factors. There was a highly significant positive correlation between Ki-67 index and both T stage (rs = 0.44, P = 0.002) and histological grade (rs = 0.60, P <0.001).
When comparing the number of poor sleepers in the different subgroups with Fisher’s exact test, there was a highly significant difference between treated SRBD patients and all other subgroups (with untreated SRBD P =0.002; with insomnia P =0.002; with RLS/PLMD P =0.008).
MI complications of VTA showed an increasing trend with age, peaking at 6.1% in patients 80 years of age and older ( P = .002).
close to significancep < 0.002
Five additional miRNAs (miR-664-3p, miR-592-5p, miR-484, miR-687 and miR-192-5p) showed expression differences which were close to significance (significance cut-off: p < 0.002).
There was also a significant trend to worse HRQoL represented by overall summary and physical dimensions scores with low TSAT ( P = 0.002 and P = 0.001, respectively), serum iron (both P = 0.03), and ferritin ( P = 0.03 and P = 0.02, respectively).
In both moderate and severe groups, condylar volume and superficial area showed a decreasing trend from T 0 to T 1 (moderate: P = 0.002, P = 0.001; severe: P = 0.001, P = 0.003), and no difference was found between T 1 to T 2 .
Multivariable logistic regression analysis revealed that an increase in fat mass percentage resulted in decreased AMVF incidence (HR: 0.83, 95% CI: 0.70–0.97; p = 0.018), while occupation (moderate or heavy work) remained a highly significant predictor (HR: 57.76, 95% CI: 4.23–788.57; p = 0.002).
The best model only included the fixed factor delay which had a highly significant effect on the monkey’s performance ( F (3, 81) = 5.33, p = .002).
Enterococcus faecalis was the most prevalent species overall and showed a highly significant association with the West region (36 isolates; p = 0.002), while also maintaining a strong presence in the Centre region (41.9%).
The disease was statistically significantly associated with other chronic DM complications such as: i) peripheral neuropathy (p = 0.001), however, the association was only marginally statistically significant when adjusted for sex and duration of disease (logistic regression adjusted OR 1.70 95% CI 0.90–3.21); ii) coronary artery disease (p = 0.002), but again was only marginally statistically significant when adjusted for sex and duration of disease (adjusted OR 1.96 95% CI 0.91–4.22); and, iii) peripheral vascular disease (p = 0.009), however, this effect disappeared when adjusted for sex and duration of disease (Table 5 ).
A correlation analysis between the staining pattern of the two antibodies revealed a highly significant correlation ( P = 0.002; r = 0.55), corroborating the validity of the staining protocol.
There was highly significant genotypic differentiation (Fisher's exact test = P<0.002, df = 14) within populations for all loci except Dicten18 and Dicten27 (Fisher's exact test = P>0.1, df = 14).
Mentalizing categories The effect of mentalizing category was highly significant, F (2, 350) = 6.54, p = 0.002.
There was also a significant trend towards increased non-HDL-C levels for APOA5 rs651821 C carriers (TT genotype: 3.01 ± 0.80 mmol/L; non-TT genotype: 3.24 ± 0.92 mmol/L; P = 0.002).
Conversely, AMH reported highly significant difference between very low AFC and with those having either normal AFC ( P = 0.002) or higher AFC ( P = 0.001).
Nevertheless, the GLP‐1‐associated selective ANGII suppression in the present study was highly significant (~30%, p = 0.002) compared to vehicle (Asmar et al., 2019 ).
There was a decreasing trend in visual acuity with increasing severity ( P = 0.002).
day 14) on survival was found to be statistically highly significant (OR: 0.42, p = 0.002).
showed a trendp =0.002
The Wilcoxon signed rank test was not significant ( p =0.086), but showed a trend pointing into the same direction as the parametric mixed-effects model, which compares mean values ( p =0.002).
failed to reach significancep = .002
By contrast, gender was not significantly associated with Cluster 1, χ 2 (1) = 5.58, p = .02, and failed to reach significance for Cluster 3, χ 2 (1) = 9.41, p = .002.
There was a significant trend ( p = 0.002) toward an increase in mean age each year, increasing by 4.4 years ( p = 0.008) over the course of the analysis.
borderline significanceP=0.002
Although the differences in quality of life scores between the intervention and control groups only achieved borderline significance on 7 and 28 days (P=0.002 and P=0.046, respectively), both groups demonstrated a gradual improvement in quality of life (P<0.001 for both groups in trend analysis; table 2 ).