Barely Significant

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Concerning the difference in immune cell infiltration between the infiltration zone and tumor core, we found a tendency towards higher absolute macrophage infiltration (CD68 + as well as CD163 + ) for the tumor core which did not reach statistical significance on a p < 0.01 level ( p = 0.017 for CD68 + and p = 0.012 for CD163 + , Fig. 2 B/C).
highly significantp=0.010.2× alphaqualifiedgold
a strong trendp=0.061.2× alphagold
Consistent with this data, there was a strong trend (Pearson correlation coefficient=0.3, p=0.06; n=40) towards a correlation between Arg ( ABL2 ) and TWIST1 mRNA expression in human melanoma metastases (Oncomine Riker dataset), 37 which became highly significant when the n was increased by including all skin cancer samples (Spearman correlation coefficient=0.29, p=0.01; n=82).
RESULTS Both groups showed improvements in negative and positive attitudes, although the reduction in scores for the negative attitude domain did not reach statistical significance in the IL + SP group (for the SP group, P = .01 and < .001, respectively; for the IL + SP group, P = .15 and .01, respectively).