Excerpts

The heterogeneity was low (I 2 = 26%) and the overall effect was highly significant (Z = 11.41, p < 0.00001).

The STRING (Search Tool for the Retrieval of Interacting Genes/proteins) functional analysis of DAPs during the 8–12 cell-to-morula transition confirmed the highly significant enrichment in the ribosome, spliceosome and RNA transport pathways (p-values < 10 −5 ; see all enriched terms during the 8–12 cell-to-morula transition in Supplementary Table S5 ).

In exploring the subgroup for tensile strength ( Table 4 ) there was a highly significant difference ( P < 0.00001) when nano filler was added to the material, however there was no significant difference when micro fillers were added ( P = 0.74). 3.1.2.

This difference, favoring the untreated patients, is highly significant ( P < 0.00001). 19 Hematomas are not inconsequential. 11 Blood transfusions should rarely be needed for cosmetic surgery patients.

The 2 mg dosage also showed a highly significant effect ( p < 0.00001, I 2 = 12%), with low heterogeneity.

A genome-wide association study (GWAS) screened 297,876 SNPs and identified highly significant associations ( p < 1 × 10 −5 ) with head smut resistance in sorghum.

Results The measurement of educational outcome was highly significant ( p < 0.00001).

This difference between the juvenile and adult volumes was highly significant ( P < 10 −5 , unpaired t test, t = 7.9, d.f. = 14, comparing trace volumes of juveniles with trace volumes of non-manipulated adult birds with n ≥ 6 HVC X /bird).

There was very highly significant difference in the marital status of the two groups of study p=0.00001; HIV+ve had more divorcees and widows than HIV-ve (8.6% vs 1.9%), (25.7% vs3.8%) respectively and 88.9% (n=24/27) of the HIV+ve widows testified that their husbands died of HIV infections.

Most babies (66/74, 89%) experienced a fall in their z -score between stoma formation and reversal, and this growth failure was highly significant ( P < 0.00001, paired Wilcoxon signed-rank analysis).

Predictive Value of the First Injection on Long-Term Outcome There was a highly significant (r = 0.855, p < 0.00001) correlation between the outcome 30 days after the first injection and the outcome after one year of continuous 3-monthly injection therapy for the pRoMs ( Figure 3 A).

The overall differences between infected and non-infected hosts according to seasons were all highly significant for both parasitic species (p≤ 0.00001).

The presence of clustered breakpoints on a per-chromosome basis 13 : chromosomes that had a highly significant non-random distribution of breakpoints with a stringent threshold of P < 10 −5 were considered to be clustered.

A z-test of the difference was highly significant z = ( .7428 - .0322 ) / ( 6.737 X 1 0 -4 ) 2 + ( .0022 ) 2 = 314.13, (P < .00001).

Four SNPs showed associations with post-RT pain at the marginal significance level of p < 1 × 10 −5 ; rs16970540 in ring finger and FYVE-like domain containing E3 ubiquitin protein ligase ( RFFL) or near to DNA ligase 3 ( LIG3 ) gene ( p = 1.7 × 10 −6 ), rs4584690, and rs7335912 in ATP-binding cassette, sub-family A, member 4 ( ABCC4)/ multidrug resistance protein 4 (MRP4) gene ( p = 5.5 × 10 −6 and p = 7.8 × 10 −6 , respectively), and rs73633565 in epidermal growth factor-like protein 6 ( EGFL6 ) gene ( p = 8.1 × 10 −6 ).

Of these 27 loci, five loci were identified as either genome-wide significant or suggestive of significance ( p < 1 × 10 −5 ) in a separate, previously published GWAS of one of the five traits. 118 loci were genome-wide significant for neuroticism, with 38 loci not identified in the univariate item-level GWASs ( Supplementary Table 6 ; Figure 1b , Figure 2b ).

At 0% the low α-diversity of phototrophs was highly significant to diversities at 20% (June) (t = −8.85, df = 12, p < 0.00001 ) and at 45% (December) intermittence (t = −8.4, df = 21, p < 0.00001 ) ( Table S5 ).

As shown in Figure 4 , the results of the right M1 group showed no significant indigenous effect ( Z = 1.04, p = 0.30), and there was still extremely significant heterogeneity (Chi 2 = 51.77, p < 0.00001, I 2 = 90%).

There was a highly significant and very strong correlation between the TRAK and the volume encompassed by the reference isodose surface volume (15 Gy isodose) ( p < 10 −5 , rho = 0.84) ( Figure 1 ). 3.3.

The figure shows a positive, highly significant relationship ( r = .620, p <.00001), between these conditions, indicating that speakers generally accept Th-R orders vP-internally to the same, typically low, degree as they do under object shift.

Chlorophyta and Toxoplasma seem to have a significant positive influence on each other ( P < .01), whereas Dictyostelium and Plasmodium seem to have a highly significant positive influence on each other ( P < 10 −5 ).

Increasing UF volume or dialysate flow led to a highly significant increase in IL-1 receptor antagonist and IL-6 clearance rates ( P < 0.00001).

In contrast, cerebrospinal fluid (CSF) volume showed a significant increase in the full penetrance group (≥40 CAG repeats) compared to the normal repeat group (≤26 CAG repeats), with a highly significant p value (*** p < 0.00001).

We found 449 genes common to both DEG sets of mouse Lhx2 cko and PRDM16 mutant organoids, which is highly significant based on hypergeometric statistics showing a representation factor 55.3 with a P -value < 0.00001 (see Methods) ( Supplementary Fig. 4D ).

All correlation coefficients between these two datasets were above 0.99 (Pearson’s r ) and highly significant with p < 1e-5.