Excerpts

This difference, favoring the untreated patients, is highly significant ( P < 0.00001). 19 Hematomas are not inconsequential. 11 Blood transfusions should rarely be needed for cosmetic surgery patients.

Results Nadi Shodhana Pranayama showed a significant decrease in ART (p = 0.01) and Bhramari Pranayama showed a highly significant decrease in ART (p < 0.00001).

For dentin permeability, the Nd: YAG laser group differed significantly from the EDTA gel group ( p = 0.0032), while the combined treatment group showed highly significant differences compared with both the EDTA gel group and the Nd: YAG laser group ( p < 0.00001).

The addition of radiotherapy therefore resulted in a substantial absolute benefit (locoregional recurrence was avoided in 17.4% of women at 10 years) as well as a highly significant relative benefit (risk ratio 0.31; P < 0.00001).

In the SA27063 × A17 F 2 population a highly significant quantitative trait locus (QTL, LOD = 7.37; P < 0.00001) named r esistance to the n ecrotroph P homa m edicaginis one ( rnpm1 ) genetically mapped to the top arm of linkage group 4 (LG4). rnpm1 explained 33.6% of the phenotypic variance in the population's response to infection depicted on a 1–5 scale and was tightly linked to marker AW256637 .

2.8 EWAS of physical activity and functional analyses At the nominally significant threshold (defined as p < 1 × 10 −5 ), we identified 7 CpGs associated with %time spent in MVPA (Figure 3a and Table S4a ), and 12 CpGs associated with MET‐Hours (Figure 3b and Table S4b ).

Dunn’s post hoc test showed highly significant differences between the intermediary and dry periods ( p = 0.00001) and between the rainy and dry periods ( p = 0.000001).

We observed a strong and highly significant overlap of 516 genes (Monte-Carlo empirical P < 10 −5 , normal approximation P < 10 −300 , Additional file 1 : SI Fig.

An rmANOVA comparing WJ-Fluency to both WJ-Basic Reading and WJ-Comprehension showed both a highly significant main effect of group ( F (1,55) = 12.8, p < 0.00001) and a highly significant group X test interaction ( F (2,54) = 5.64, p = 0.006), with significant differential deficits of Fluency vs. both Basic Reading ( F (1,55) = 8.43, p = 0.005) and Comprehension ( F (1,55) = 10.9, p = 0.002).

A resampling analysis shows that the difference is highly significant ( p < 10 − 5 , see Methods): there is thus an overall enrichment of West Asian ancestry in regions under selection.

With the exception of “CSF-Aβ38” and “CSF-Aβ40” all showed strong and highly significant association with markers in the APOE region but no better than suggestive ( P < 1E-05) signals in the remaining genome (see Supplementary Figs. 3 – 7 and Supplementary Tables 7 – 11 ).

This difference was highly significant when comparing each AUC avg group with placebo group ( P < .00001, Tukey test).

Results The values of LV-EDV and LV-ESV measured in 3D-ECHO showed highly significant correlations with CMR (for LV-EDV r = 0.892, p < 0.00001; for LV-ESV r = 0.896, p < 0.00001).

Despite this heterogeneity, the overall effect size is highly significant ( Z = 30.91, p < .00001).

The functional cluster F1 (Left Superior Temporal gyrus + Cingulate Gyrus + etc., see Table 3 ) was highly significant ( p < 10 −5 ) with all structural clusters.

The comparison between the IUGR group and other patients regarding abnormalities in UA PI was highly significant ( P value < 10−5); 13 out of 60 individuals in the IUGR group had UA PI above the 95th percentile, compared to only 1 out of 100 in the other patients.

The apical recurrence rate was reduced from 52% to 15% (SD 10.7%), which is also highly significant, p < 0.00001, as was the reduction in the posterior compartment recurrences–31% reduced to 10% (SD 10.2%) with p < 0.00001.

Principal component analysis (PCA) further confirmed distinct microbial community structures between groups, The PERMANOVA analysis revealed a highly significant difference between the two groups ( p = 0.00001) ( Fig. 1C ).

All differences were statistically highly significant ( p < .00001).

For example, the differences in −6 nucleotide frequencies between our data set and the reference panel were highly significant (p<0.00001), yet the preference for guanine did not change; rather, the strength of the preference increased while the use of thymine at this position decreased in our refined panel.

2b ), but, when accounting for differences in site location, there was a highly significant difference in the mean percentage of ARB for the antibiotic types (χ 2 =25.5, df=2, P =<0.00001) ( Fig. 2c ).

Twelve novel loci showed a trend of association with V̇O 2 peak response that reached suggestive significance ( P < 1 × 10 –5 ).

In contrast, a highly significant increase in midbody-flanking Sept2 ( p -value < 0.00001) and a corresponding decrease in Sept2 at the central midbody ( p -value < 0.00001) were detected relative to the Jurkat CypA+/+ cells ( Figure 1 E).

Correlation of CDX2 with clinicopathological parameters CDX2 expression was inversely associated with lymph node metastasis (high CDX2 expression was associated with decreased lymph node metastasis (RR=1.52, 95% CI: 1.29-1.79, P<0.00001) ( Figure 5 ) however, CDX2 expression was significantly higher in poorly differentiated gastric cancers (RR=1.52, 1.52; and significantly higher in well-differentiated and latent gastric cancers marginal significance compared with 95% CI: 1.22-1.87, P<0.00001) ( Figure 6 ) was observed (RR =0.82, 95%).CI =0.67-1.01, P=0.07) ( Figure 8 ).

The unpaired Student’s t-test revealed a highly significant difference in PNP biodegradation between the compared conditions, with a p-value < 0.00001, indicating statistical significance well below the 0.01 threshold.