Excerpts

The results of ANOVA analysis showed highly significant ( P<0.0001 ) variances of genotype ( G ), environment ( E ) and genotype × environment ( G × E ) interaction for the SOC ( Table 1 ).

This at some points would also clarify how the statistics were computed exactly (e.g., "All subjects showed comparable difference and the difference in medians evaluated across subjects was highly significant (p<<0.0001).", p.10, is ambiguous to me).

2 ), post-hoc analysis showed a highly significant reduction in average counts between interval 1 and both intervals 2 and 3 (both p < 0.0001 after Bonferroni correction).

Functional groups displaying highly significant ( P < 0.0001) increased expression included mitochondrion, oxidative phosphorylation and fatty acid metabolism while functional groups with decreased expression were mainly associated with structural genes and included the sarcoplasm, laminin complex and cytoskeleton.

It is evident from the table that all the paired comparisons showed highly significant difference of means ( p < 0.0001), except Group II and III ( p = 0.4573).

As shown in Table 2 , the model selected by the test was highly significant ( p < 0.0001).

This difference was highly significant ( p < 0.0001).

Post hoc paired t-tests confirmed highly significant improvements at 1, 3, and 6 months (all p < 0.0001).

In both groups, there was a significant trend towards progressive clearance of thrombotic masses from the vessel lumen ( p < 0.0001 for within-subject effect “time”).

The incidence was 7.9% (79 of 994) in statin group and 14% (140 of 992) in control group, demonstrating that high-dose statin therapy preloading before PCI had a favorable trend toward the following outcome and reduced the incidence of MACE (OR=0.53, 95% CI: 0.39 to 0.71, p<0.0001) ( Figure 5 ).

Following stimulation with CMV pp65, correlations were highly significant for IFN-γ and IL-21 ( r = 0.53, p < 0.0001) and IL-22 and perforin ( r = 0.50, p = 0.001) ( Figure 3 a).

Overall, treatments were highly significant ( F = 12.53; df = 6; p < 0.0001), causing greater mortality of all D. suzukii life stages (larvae at 4 DAA, pupae and adults at 10 DAA) than the control, with excellent activity (above 90%) in 3.5 × 10 8 and 3.5 × 10 7 cells mL −1 treatments, while the others showed fairly good efficacy of more than 60%.

For the Mania Scale, two-way repeated measures ANOVA with covariance for baseline showed a highly significant effect of time (F = 16.0, df = 2, 28, p < 0.0001) and a significant interaction of time and side of TMS (F = 5.2, df = 1.4, 19.2, p = 0.04, Greenhouse-Geisser-corrected).

Statistical evaluation indicated that the difference in the staining intensity of the different populations of CD-immunoreactive cells was highly significant (one-way ANOVA, for CD34, F (18.306) = 389.861; P<0.0001 and for CD38, F (2.633) = 2573.162; P<0.0001).

This linear regression had a high fraction of variance explained by the model, R 2 = 0.86, with all points falling within or very close to the 95% confidence intervals (Figure 1C ), and a highly significant p-value of P < 10 −4 based on a permutation test ( 48 ).

On the 9th day, a highly significant difference was observed between the control and CCl 4 groups ( p < 0.0001).

The p -value represented the level of significance of the data, with p ≤ 0.05 (*) considered significant, p ≤ 0.01 ** as very significant, p ≤ 0.001 *** as highly significant, and p < 0.0001 (****) as most significant. 3.

RML-inoculated transgenic mice reached terminal disease after 400 ± 56 dpi (n = 10), whereas WTPrP C mice became terminally sick at 155 ± 1.6 dpi (n = 8), thus also showing a highly significant delay for PrP C GPIThy-1-expressing mice (Log Rank (Mantel-Cox)**** p <0.0001; S6A Fig ).

These appear in Table 9 , which is highly significant ( P = 0.0001).

A highly significant knockdown efficiency of murT was found with sgRNA1- murT comparing with WT ATc (53.5-fold; P < 0.0001), PLJR962 ATc (44.6-fold; P < 0.0001) or the respective uninduced mutant (57-fold; P < 0.0001).

Of the four SNPs with significant or borderline significant IL-2 associations in the whole blood assay, only rs10507173 was associated with CD4+ IL-2 production ( p <0.0001, general linearized model), though the association was driven by a single minor allele homozygote outlier (2H) and was not significant under a dominant model ( p = 0.95).

While immunohistochemical analysis of 47 patients demonstrated a highly significant association between high Snail expression and poor survival ( P < 0.0001) [ 118 ], SNAI1 mRNA levels from the GDC portal ( https://portal.gdc.cancer.gov ) showed no significant correlation with patient outcomes (Fig. 2 ).

Overdose recovery time is highly significant ( P < 0.0001) between the Naloximeter and self-recovery ( N = 3 and 4; recovery times = 4.5 ± 0.3 and 23 ± 4 min, respectively).

The trophozoites treated with nitroxoline showed a highly significant decrease in ATP levels compared to the negative control, p < 0.0001 (****) ( Figure 7 ).

There was a highly significant difference between the infection rates of woodpigeons with S. calchasi across federal states (p < 0.0001).