Barely Significant

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a significant trendp < 0.00010.0× alphagold
At the anterior end of the inflection point, there was no significant trend in current asthma risk with increasing log 1-Hydroxynaphthalene [0.90 (0.65, 1.25), p = 0.5418], whereas there was a significant trend in current asthma risk with increasing log 1-Hydroxynaphthalene at the posterior end of the inflection point [1.46 (1.27, 1.68), p < 0.0001].
highly significantP <0.00010.0× alphaqualifiedgold
In contrast, 12 of the 43 (B6× Ads )F 2 progeny exhibited the white-spotting phenotype, showing a highly significant deviation from the expected 2:1 ratio for a simple autosomal dominant inheritance pattern with homozygous embryonic lethality (χ 2 =29.07, P <0.0001).
moderately significantp < 0.00010.0× alphaqualifiedgold
Interestingly, lesion location and gender—only moderately significant in univariate analysis (Cramér’s V = 0.2967; OR = 0.193, p < 0.0001, Table 2 )—gained weight in glmnet, suggesting interaction effects or dependencies not captured in univariate tests but revealed through multivariable modeling. 5.
highly significantp < 0.00010.0× alphaqualifiedgold
The minor allele frequency of rs2607474 in the methylated group was significantly lower than that in the unmethylated group (p = 0.0004, setting α = 0.05, 1-βpower = 0.946) and the frequency of the GG homozygote was significantly higher in the methylated group than in the unmethylated group (p = 0.013). Risk associated with rs2607474 GG homozygote for DAPK and CDH1 methylation Overall, rs2607474 GG homozygote conferred a highly significant increased risk for the development of DAPK methylation (OR, 2.43; 95%CI, 1.60-3.69; p < 0.0001; Table 4 ).
highly significantp < 0.00010.0× alphaqualifiedgold
Intraclass correlation analysis for somatic signs showed an estimate for heritability of 0.668 in mecamylamine treated animals and 0.318 in saline treated mice, consistent with the highly significant increase ( p < 0.0001) in somatic signs caused by mecamylamine treatment of nicotine‐exposed mice (11.82) versus saline treatment (3.24).
highly significantP < 0.00010.0× alphaqualifiedgold
In comparing the GRC and f (s.lys) of Bcc phages, we found a highly significant (R 2 = 0.67; P < 0.0001) inverse relationship between these values for most phages which exhibited at least moderate (GRC ≥ 0.05) antibacterial activity ( Fig. 5A ), demonstrating that low- f (s.lys) LC Bcc phages can have high GRC values and may therefore be therapeutically suitable.