Excerpts

One-way ANOVA showed highly significant difference across the mean ( p < 0.0001) (Tables 1 and 2).

They found a small, but highly significant, decline in the strength of reported correlations with publication date (best model: P < .0001; R = -0.133) and with sample size (best model: P < 0.002; R = -0.188).

Eighty-seven per cent of markers in the CEPH data and 83 per cent of markers in the NASC data had greater heterozygosity than the corresponding marker in the Samoan data; a sign test showed that both of these differences were highly significant ( p < 0.0001 for both tests).

Strikingly, for both protocols involving the injection of microbubbles, the peak amplitude displayed a highly significant increase, leading to 12 ± 2% (p < 0.0001) increase in PA for the thinned-skull and 9 ± 2% (p < 0.0001) PA increase in the transcranial configuration, as compared to the control imaging protocol (unpaired Student's t -test).

Choice of PD methods From 1983 to 2012, we found a clear trend toward increased number of PD patients undergoing automated peritoneal dialysis (APD) (p < 0.0001).

The fecundity of laboratory reared females showed a highly significant positive relationship with female body mass before egg laying (linear regression, y = −6.484+2363.95 x , F 1,13 = 86.9, R 2 = 0.82, P<0.0001).

Results We observed a highly significant decrease in the presence of the KIR2DS2 and KIR2DS4 genes (OR = 0.15, 95% CI = 0.05-0.41, P = 0.0001; OR = 0.06, 95% CI = 0.02-0.2, P = 0.000, respectively) and in the presence of the KIR2DL5A gene (OR = 0.05, 95% CI = 0.02-0.14, P = 0.0000) in the TC group compared to the HC group.

By aggregating the two subgroups with low risk and three subgroups with medium risk, patients could be assigned to three risk groups (high, medium, low) with a highly significant ( p < 0.0001) five-fold difference in risk (Table 5 and insert in Fig. 2 ).

In particular, a highly significant ORR was seen in patients who developed skin disorders ( P = 0.0001), vitiligo ( P = 0.0004) and thyroid dysfunctions ( P = 0.0127) ( Supplementary Table S4 ).

The correlation of health practices related to vitamin D status with dental caries was highly significant ( p = 0.0001), and lesser exposure to sun was also significant ( p = 0.002) ( Table 2 ).

A highly significant QTL (p < 0.0001) was detected on chromosome Z between microsatellite markers MCW258 and MCW241 (at 21.40 Mb and 34.26 Mb, respectively) [see Additional file 1 ].The effect of this locus was 15.28 HU.

The wear rate showed a statistically highly significant difference between the two liners after 12 ( p < 0.0001), 18 ( p = 0.018) and 24 ( p = 0.002) months (Fig. 5 , Table 2 ).

The chi-square test of likelihood ratio was highly significant (χ2 = 782.15, p < 0.0001), indicating the model’s overall fitness.

Additionally, acarbose significantly reversed IGT to NGT; an effect that was highly significant when compared to the placebo group (p<0.0001).

After excluding asystole patients with presumed CO = 0 L/min, the association between PetCO 2 and CO remained highly significant ( P < 0.0001).

Total facility time was reduced by 48 min and costs were 39.35% lower in the ES group, with all comparisons showing highly significant differences ( p < 0.0001). cost analysis drug‐induced sleep endoscopy hypoglossal nerve stimulation obstructive sleep apnea procedure efficiency 2.5 Discussion Drug‐induced sleep endoscopy can be efficiently and safely performed in the endoscopy suite in a cost‐effective manner.

Of note, there was a highly significant relationship between UH and CNOC status with most departments having the status of both (n=24/72) or neither UH nor CNOC (n=31/72; p<0.0001; Table 1 ).

The intercept was highly significant ( P < 0.0001), with an estimate of 98.25, suggesting a strong baseline relationship with PLR levels.

The correlation coefficients among these three indicators are rather high: 0.31 between anxiety and loneliness, 0.21 between uselessness and loneliness, and 0.18 between uselessness and anxiety; all of them are highly significant (p < 0.0001).

The Top ICH genes had highly significant and similar associations within the primary cluster that included intratumoral densities of CD45 + (r = 0.53–0.67, all p < 0.0001), CD8 + T cells (r = 0.48–0.71, all p < 0.0001, Fig. 3 B), CD20 + B cells (r = 0.47–0.56, all p < 0.0001), and CD138 + cells (0.37–0.5, all p < 0.0001, Additional file 1 : Table S1).

For each of the RD scores and for the DLQI, repeated measures analyses considering group, treatment week (as an ordinal variable, 0–7) and the group–week interaction identified a consistent, highly significant ( p < 0·0001) association between outcome score and treatment week, with significantly and increasingly higher scores over time.

Moreover, the observed extremely significant difference (p = 0.0001) showed the gap between generations and the decline of indigenous knowledge on medicinal plants down generations.

Specifically, the OR were as follows: NHHR (OR: 3.34, 95% CI: 2.79–4.01), RC/HDL-C (OR: 2.45, 95% CI: 2.06–2.91), TC/HDL-C (OR: 3.34, 95% CI: 2.79–4.01), TG/HDL-C (OR: 2.75, 95% CI: 2.30–3.29), and LDL-C/HDL-C (OR: 2.92, 95% CI: 2.44–3.50), all demonstrated a significant trend ( P <.0001).

There was a highly significant effect of time (F (5, 153) = 12.80, p < 0.0001) and treatment (F (1, 34) = 4.892, p = 0.0338), but no significant interaction (F (5, 153) = 1.584, p = 0.1677) over the 6-week period indicating that the animals learned the rules of the task, with anthocyanin-rich extract fed animals performing better than the control fed animals.

Interestingly, we found a highly significant positive correlation between KI67 LI and TUNEL levels both at baseline ( Figure 3 ) and surgery ( Figure 4 ) (Spearman's ρ =0.5 and 0.6, respectively, P <0.0001).