Excerpts

Applying the aforementioned post hoc ANCOVA sensitivity analysis, the treatment effect defined by the primary outcome measure remained highly significant ( p < 0.0001).

Models generated for different quality attributes of instant phirni dry mix were highly significant ( p ≤ 0.0001).

Highly significant positive associations were observed between the severity or category of ultrasound and sialendoscopy findings for first and last examinations for PGs (both p = 0.0001) and SMGs ( p = 0.002; p = 0.037).

Furthermore, we found a highly significant, negative correlation between PBR values and RBC filling (Person r = − 0.87, p < 0.0001) (Fig. 2 c).

Hence, a highly significant difference was detected between the algometric measurement before and after treatment was detected ( p <0.0001, Fig. 3 B).

Further, the IBC treatment at 5 μM and 10 μM concentrations showed a highly significant (p < 0.0001) reduction of speck formation in cells, in comparison to the cells induced with ATP, indicating reduced oligomerization ( Supplementary Figures S2E, F ).

Thermal Detection Thresholds ANCOVA with age as a covariate (partialing out the highly significant age-related effects) revealed a highly significant effect of group (F 2,113 = 30.04, p<<0.0001), body side (ipsilateral vs. contralateral: F 1,113 = 12.39, p<0.001) and group x side interaction (F 2,113 = 4.65, p<0.05) for the cold detection threshold (CDT).

Dance-compound introduction resulted in a highly significant increase in the number of dance bouts versus the solvent control (t = 5.16, d.f. = 39, Tukey-Kramer adjusted p<0.0001).

There was a highly significant association between TIA-1+ and Granzyme B+ cells (p<0.0001).

This statistical calculation model with backward elimination of non-significant markers showed a highly significant overall model fit ( p < 0.0001) with logit (p) = −0.367 + 4.148 * miR17a −0.397 * miR20a.

The difference between the groups was highly significant ( P < 0.0001), reinforcing LDAR as a robust prognostic biomarker for ICU mortality in septic patients with malignancies.

The model was highly significant (F = 117.22; p < 0.0001) and accounted for 82.4% of the variance in planned spending (R 2 = 0.824).

Nominally significant MetaXcan results ( p < 10 −4 ) were investigated using gene set enrichment analysis. 2.8 Look‐Up of Results From Prior WL in COPD GWAS We compared significant results from our prior GWAS of WL in COPD [ 9 ] with results from the current analyses.

All quadratic terms were similarly highly significant ( p < 0.0001), with glycerol 2 (F = 197.9) being the strongest factor, followed by peptone 2 (F = 221.5) and pH 2 (F = 181), suggesting a curvilinear parameter–pyocyanin yield relationship in each case.

In 12,899 patients, the improvement in the ROC curve area of APACHE III compared with APACHE II was highly significant (P < 0.0001).

P < 0.05 was considered statistically significant (*), P < 0.01 very significant (**), P < 0.001 extremely significant (***), and P < 0.0001 extremely significant (****).

Here, we found that sAPPα (1 nM, 2 h) induced a highly significant increase in newly synthesized Arc protein in both the dendrites (2.72 ± 0.41, p ≤ 0.0001; Figures 3C–E ) and somata (1.69 ± 0.32, p = 0.03) of cultured hippocampal neurons.

The mean absolute increase in lumbar BMD in the 13 patients in whom the increase was ≥ the LSC, was 0.062±0.036 g/cm 2 resulting in a percent increase from baseline of 7.8±5.9% (range; 2.4-21.5%) and there was a highly significant difference (P<0.0001, power 99.9%) between the pre and post VNS lumbar BMD in these patients.

Survival analysis revealed highly significant differences between high-risk and low-risk groups (p < 0.0001) (Fig. 5 A), with ROC curve values at multiple time points exceeding 0.7 (Fig. 5 D).

We find a highly significant correlation between p53 protein synthesis in leukemic blast cells and the secondary plating efficiency of these cells (p = 0.0001).

Two-way ANOVA analysis showed a highly significant effect of stress on body weight gain [ F (1, 147) = 16.25, P < 0.0001], with a highly significant effect of day [ F (13, 147) = 6.617, P < 0.0001].However, Bonfferoni’s post hoc test showed no significant interaction between stress and day on body weight gain [ F (13, 147) = 0.468, P = 0.9393] ( Figure 3A ).

The consistent differences between males of different ecotypes, with stream males generally scoring higher on PC1, remained highly significant (F = 25.9093, P<0.0001, df = 1, 110).

Two-way analysis of variance indicated a highly significant (p<0.0001) reduction of 46% in 125 I-SI Ang II binding in the brains of the neurolysin knockout strain.

Effects of miR-485 on NOI were highly significant by one-way ANOVA ( F 4,25 = 26.15, p < 0.0001).

The estimated variance components for genotype were highly significant (P<0.0001) at both seedling and adult plant stages ( Table 1 ).