Excerpts

22 - 26 For DCIS components, in a prospective study by Kuhl et al 29 on 593 consecutive women with invasive cancer, the sensitivity advantage of MRI over mammography plus ultrasound for depicting DCIS components was highly significant ( P < .0001) and increased with increasing relative size and increasing nuclear grade of DCIS components.

SRCV and VP demonstrated a highly significant upregulation for IFIT1 , MX1 , APOBEC3G and MX2 as compared to late but not early treated individuals ((SRCV: p < 0·0001, p < 0·0001, p < 0·0001, and p < 0·0001, respectively) and (VP: p < 0·0001, p < 0·0001, p = 0·006, p = 0·0002, respectively; Fig. 2 )).

The spatial variability of Rhodes grass productivity was observed to be of the same trend as indicated by the highly significant spatial correlation between the CNDVI values of the first and second harvests, with a correlation coefficient ( r ) of 0.74 ( p = 0.0001).

The rate of perinatal death was found to be highly significant (p<0.0001) with the number of children a woman had in both survey rounds.

The small subgroup of current smokers ( n = 4) showed a somehow peculiar profile, with highly significant changes in the expression of ICAM1 and NFKB1 ( p < 0.0001 and p = 0.002 respectively) and some other minor variations.

In case of HaCaT cells, highly significant viability differences were observed between control, ZnPc or TMPyP versus combination-treated cells ( P <0.0001) at both post-treatment times.

General combining ability (GCA) and specific combining ability (SCA) effects were highly significant ( P < 0.0001) for all traits.

Adding calcium was associated with a highly significant reduction in SLS prevalence from about 60% without supplemented calcium to 15% in high and medium calcium-supplemented treatments (P < 0.0001, Fig 2 , Table 1 ).

Note that all regional changes in WM volume in Figure 2a,b are highly significant ( p < .0001) except for the frontal pole (no change at p < .05 from 9 to 11 years; decrease at p = .0058 from 11 to 13 years).

This difference was highly significant using a paired t-test with data points paired by year (P<0.0001, df = 11).

This yields a highly significant model ( p < 0.0001) and three PCs that collectively explain 94.7% of the variance (Table 2 ).

4 B C = 82.39 + 1.11 e - 5 C - 87.96 d - 1.44 t - 0.61 e - 5 C d - 0.01 e - 5 C t + 1.83 d t + 10.28 The prediction model was highly significant (p < 0.0001).

spiralis , respectively), and were highly significant in all cases ( P <0.0001).

A quantitative analysis on day seven revealed highly significant differences in the number, size and roundness of the spheroids generated by D5 cells compared to control NIH3T3 cells ( p < 0.0001) (Fig. 3 b).

For ratings of the extent to which a speaker was being ironic, there were highly significant main effects of Statement ( F (1,32) = 87.7; p <0.0001, η p 2 = 0.72) and Occupation ( F (1,32) = 13.5; p = 0.0009, η p 2 = 0.30), as well as a significant Statement X Occupation interaction ( F (1,32) = 8.2; p = 0.007, η p 2 = 0.20), a group X occupation interaction ( F (2,64) = 4.2; p = 0.047, η p 2 = 0.11) and a significant Statement X Occupation X Group interaction ( F (3,96) = 5.0; p = 0.032, η p 2 = 0.13).

The test for heterogeneity was highly significant [ Q ( df = 34) = 577.47, p < 0.0001].

One study reported a significant difference (MD: 25; 95% CI: 18.16–31.83; P = 0.0001), 27 , 30 and another found a moderately significant benefit (MD: 10.2; 95% CI: 5.91–14.48; P = 0.0001). 27 , 30 Two studies showed no significant differences ( P = 0.1622 and P = 0.2223, respectively). 26 , 36 Physical Well-being of the Chest The results were heterogeneous.

According to the linear mixed-effects model, the covariance parameter estimates for residual variance were highly significant (Z = 4.415, p < 0.0001), indicating a good fit for individual variability.

Despite the differences in strength, all correlations were highly significant (p < 0.0001).

NAFLD incidence rates across groups were 2.44% (1.83%–3.05%), 5.08% (4.21%–5.95%), 9.11% (7.97%–10.25%), and 18.13% (16.61%–19.65%), demonstrating a significant trend of increasing NAFLD risk with higher LCI ( p < 0.0001).

All subjects lost ≥3.0 kg total body weight, with an average reduction in BMI of −1.14 kg/m 2 which was highly significant (one sample t ‐test, p ≤ 0.0001).

These findings of higher K/T ratios and higher pro-inflammatory activity in our population compared to populations from developed countries, coupled to the highly significant positive associations found between the K/T ratios and inflammatory activity, especially IFN-γ (neopterin: r = 0.514; p < 0.0001; IL-6: r = 0.354; p = 0.0007; IFN-γ: r = 0.344; p = 0.001), and the negative associations between IFN-γ and tryptophan ( r = −0.217; p = 0.036), strongly suggest higher levels of inflammatory activity, leading to a higher rate of tryptophan oxidation in the kynurenine pathway, to be a major contributor to the lower tryptophan levels found in the black, low income, sub-Saharan population of this study than in HIV/AIDS populations from developed countries.

However, these percentages are 10-fold higher than in healthy donors ones (0.02%) with highly significant p values of < 0.0001 for CD4 and p=0.0002 for CD8+ T cells, emphasizing the robustness of our results at this very early stage of viral infection.

The difference between the rate of episodes with no MVPA in team and individual sport was highly significant (p<0.0001); so is the sex difference in the rate of zero-MVPA episodes within individual sport, though not team sport.

Thus, elimination of T-bet results in a highly significant reduction (P < 0.0001 by Student's t test) of BGVs and autoimmune diabetes.