Barely Significant

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highly significantP < 0.00010.0× alphaqualifiedgold
The results showed highly significant (( P < 0.0001) linear correlations ( r = 0.9784–0.9907) between the Trp values determined by GC and HPLC for both the low-normal and normal-high ranges (data not shown) and between the Trp values determined by GC and the standard fluorimetric method ( r = 0.9774) (Fig. 2 ).
a decreasing trendp < 0.00010.0× alphagold
an increasing trendp < 0.00010.0× alphagold
This analysis showed an increasing trend for TPs using the filgrastim biosimilar (from 34.4% in July 2015 to 49.8% in June 2016; p < 0.0001) compared with a decreasing trend for TPs using lenograstim (from 22.6% in July 2015 to 12.3% in June 2016; p < 0.0001) and pegfilgrastim (from 26.8% in July 2015 to 20.6% in June 2016; p < 0.0001).
highly significantp <0.00010.0× alphaqualifiedgold
However, the past five-year trend (2015-2019) was different where, the daily average of PM 2.5 and PM 10 levels (2015-2019) were higher by 70 and 155% when compared with the same time period in 2020 (Phase I), which was highly significant (Kruskal-Wallis test, p <0.0001) (Fig.
highly significantp<0.00010.0× alphaqualifiedgold
When comparing the choice frequency in the two geometrically correct (C, R) versus the two geometrically incorrect corners (N, F) a highly significant difference was apparent (F(1,9) = 61.714 p<0.0001), revealing more choices for the two geometrically correct corners (C,R).
highly significantp < 0.00010.0× alphaqualifiedgold
Highly significant main effects of cell line (F = 428.7, p < 0.0001), ICG concentration (F = 312.4, p < 0.0001), and time after irradiation (F = 189.6, p < 0.0001), a significant line × concentration interaction (F = 67.3, p < 0.0001) confirmed the difference in sensitivity.
highly significantp = 0.00010.0× alphaqualifiedgold
Permutational multivariate analysis of variance confirmed that compositional differences among the three associations were highly significant (F = 7.658, p = 0.0001, 9 999 permutations), a result corroborated by the rank-based test of similarity ( R = 0.6135, p = 0.0001).
highly significantP < 0.00010.0× alphaqualifiedgold
The formation of these highly significant, cohesive subnetworks (all P < 0.0001) indicates that the candidate targets for each disease are not randomly distributed but form core functional units within the human interactome, thereby supporting their biological relevance to the respective pathophysiology.
highly significantp<0.00010.0× alphaqualifiedgold
The comparison of pre- versus post-flight values revealed that bodyweight increased in the flight group (8%, p = 0.0010), ground control (4%, p = 0.0456) and control vivarium groups (11%, p<0.0001) with overall effect of “time” being highly significant (F(1,104) = 59.79, p<0.0001).
highly significantp ~ 1e-40.0× alphaqualifiedgold
While MEASSA’s performance advantage is most pronounced and highly significant (p ~ 1e-4) against simpler algorithms like SCA, GWO, and its predecessor ASSA, it also maintains a clear and statistically significant edge (p < 0.05) over its closest competitors, mJS and PSO-ACO, which show the smallest yet still definitive p-values (p ~ 1e-2 to 1e-3).