Excerpts

No significant differences were found for Chao richness means between non-pregnant (585 ± 340) and pregnant ewes (509 ± 154), but variance differences were highly significant (F = 4.87; p = 0.0006).

The induction of CXCL8 and CXCL9 were highly significant in HSM ( p = <0.0001) as well as HSE ( p = 0.0006 and p = <0.0001, respectively) (Fig. 2a–b , Table 2 ), but the CSF-serum gradient was much more pronounced in HSM (factor of 40 and 12, respectively) compared to the HSE patient group (factor of 2.6 and 3.8, respectively) (Table 3 ).

The enrichment was highly significant and robust, and dependent on both the 33 genic and 38 intergenic insertion sites of the three species (1e-05< P <0.0006; Table 1 and Supplementary Data 3 ).

Interestingly, we observed a decreasing trend in the correlation coefficient between germline variant burden and somatic mutational burden (Jonckheere-Terpstra test, P = 0.0006; Fig. 2d ).

However, the interaction with radiotherapy was highly significant ( p = 0.0006).

Given that these patients exhibited the most pronounced alterations in PCSK9 and sLDLR levels, the correlation of the PCSK9/sLDLR ratio with the presence of ≥ 5-cm metastases was also examined, revealing a highly significant correlation ( r = 0.4527, P = 0.0006), and difference of this ratio between patients without and with ≥ 5-cm metastases (3.21 ± 1.41 vs . 1.68 ± 0.62, P = 0.0006, Fig. 2 D).

This produced just one highly significant cluster in the dorsomedial prefrontal cortex (left superior frontal gyrus, BA9; p = .0006 adjusted; see Figure 2 .

The difference was highly significant for total species richness ( χ 2 = 11.921, P = 0.0006) and exclusive species richness ( χ 2 = 42.667, P = 0.0001) but was not significantly different for the richness of plant families ( χ 2 = 1.463, P = 0.2265, Figure 3 ).

FHO/RP ratio did not present significant differences in yellow-green light conditions in between groups comparison, whereas in infrared light condition the comparison between groups showed a highly significant difference (p = 0.0006) with a larger ratio in Control Group (1.055) compared to TMD Group (0.967) ( Table 2 ).

The 24‐month LS meta‐analysis with five paired comparisons in 885 adolescents showed a highly significant weighted mean BMD difference of −0.02 (95% CI: −0.03 to −0.01) g/cm 2 in CHC‐exposed adolescents ( P = 0.0006).

When we explored the correlation between LDLc‐score and LDL‐C levels in subjects who were FH/M+ or FH/M−, a positive trend was observed among subjects who were FH/M− ( R , 0.13; P =0.0006) that was even more marked among subjects who were FH/M+ ( R , 0.15; P <0.0001) (Figure 3 ).

Association between smudge cell percentage and other prognostic factors The percentage of SC was inversely associated with lymphocytosis: a decreasing trend in the lymphocyte count was observed when the SC percentage was high (>30%) ( r = −0.51; p = 0.0006) ( Figure 2 A).

In the dominant model, carriers the C allele indicates protection to malaria, carriers of the C allele were compared to individuals with the T allele, and the difference is highly significant (OR 0.52 [95% CI 0.37–0.76]; p = 0.0006).

Differences in survival times of rMVAGnGc were highly significant (χ 2 = 17.48; df = 3; p = 0.0006). 3.3.

This correlated with a highly significant difference in the frequency of antithrombotic drug usage in the older patients ( p = 0.0006).

Effect of treatment, landscape diversity, and prairie vegetation on the bee community Regression analyses with the presence or absence of prairie strips and Shannon landscape diversity as independent variables indicated that strip treatment had a highly significant effect on the abundance of all bees ( Fig 3a and S6 Table ; p = 0.0006), 8 common bees ( Fig 3b ; p = 0.0014), 9 common bees ( Fig 3c ; p = 0.0022), and uncommon bees ( Fig 3d ; p = 0.0002).

Ordinary one‐way ANOVA followed by Tukey's multiple comparisons test was performed to compare the amount of mGluR‐LTD in the four different conditions (control; roscovitine; LP‐211; LP‐211 + roscovitine, Figure 1c ), confirming a highly significant difference (*** p = 0.0006).

A contingency χ 2 -test revealed highly significant ( p = 0.0006) statistical comparison of the exclusive variants in the patient population to those in the control group.

As expected, all of these findings were accompanied by a highly significant difference in overall survival between the CTC groups (57.9 months for patients with CTCs <5 CTCs/7.5 ml versus 27.3 months for those with ≥5 CTCs/7.5 ml; P = 0.0006).

The treatment group showed highly significant improvement compared to the placebo group in terms of both the total symptom score ( p < 0.0006) and total diagnosis score ( p < 0.003).

The differences in FLA value between alleles OsFLA6 AA and OsFLA6 GG were highly significant (Welch's t -test; P = 6.06E−04) ( Figure 3E ).

As shown in Table 6 , for CVMI, the p-values were highly significant in females ( p = 0.00061) and males ( p = 0.00371).

The difference between experimental conditions was highly significant (W = 88, p = 0.00061).

In addition, when Subtype 2 was compared with all other subtypes combined, a highly significant survival difference is still observed (log-rank test, P = 0.00061).

First, in our NSG study the difference between MmuPV1+DMBA and mock+DMBA groups was highly significant ( P = 0.00061), and no NSG mice treated with DMBA alone developed HSIL or cancer by the study endpoint.