Excerpts

As shown in Figure 4 A, decreasing number of ANCs showed a trend of a negative correlation with elevated levels of CXCL1 (r = −0.2378, p = 0.0008), CXCL2 (r = −0.2542, p = 0.0051), and IL-6 (r = −0.3428, p = 0.0001).

( 3 ), these haplotypes were shown to have a highly significant ( p -value < 0.0008) effect on sheep BW.

3 explains this behaviour of HAM scores [all p values obtained by paired (red) or unpaired (black) Student’s t tests]: in patients, the difference between pre- and post-treatment values is highly significant ( p = 0.0008), while in controls there is practically no effect of treatment ( p = 0.68).

In our study, sVAS was confirmed to be an easy and quick tool to assess olfaction and to discriminate between normal and reduced sense of smell as demonstrated by a moderate correlation with all the S'S scores and a highly significant difference in the sVAS results between normosmics and dysosmics with a small effect size ( p = .0008; d = −0.34).

Mantel tests [ 27 ] of the significance of correlations between matrices of (i) pairwise population differentiation at the LWS locus, (ii) pairwise difference in water transparency, and (iii) pairwise geographical distance, revealed a highly significant positive correlation between LWS divergence and transparency (cross matrix correlation 0.80, p = 0.0008), but only a weak correlation between LWS divergence and geographical distance (0.55, p = 0.04), and an even weaker correlation between transparency and geographical distance (0.42, p = 0.08).

There was an increase in expansions over the No RFB level for the Weak RFB condition that was highly significant at the 6.7 kb location (p = 0.0008; Fig 1C ).

A linear test-for-trend based on the log-rank test (Tarone, 1975) yielded a highly significant P value (x2= 11.2, P=0.0008).

However, gamma coherence showed highly significant increases during choice compared to must-touch between mPFC and vCA1 ( Figures 1 G and S3 B; mPFC-vCA1 t(3) = 13.760, p = 0.0008), similar to changes reported from T-maze DNMTS tasks. 18 , 19 In addition we found marginal increases in gamma coherence between nRE and vCA1 ( Figure 1 G; nRE-vCA1 t(2) = 3.272, p = 0.082).

Nevertheless, ANOVA across the three biomarkers of neural cell development indicated highly significant differences among the three groups ( p < 0.0008) that depended both upon the specific measure and brain region (treatment × measure × region, p < 0.0002).

We chose asthma nonetheless for its status as the most prevalent atopy in SIgAD patients (19.1%) [ 18 ], its highly significant GPS test statistic (p = 0.0008), and our access to a highly-powered asthma GWAS for use as an auxiliary data set ( Supplementary Table 1 ).

This difference was highly significant ( p = 0.0008).

These proportions were highly significant by nonparametric test of trend (p=0.0008), but only the severe COVID-19 group reached statistical significance vs.

The combination of buparlisib and RT in UT-SCC-15 showed the greatest growth delay and the combination was highly significant (p = 0008) compared to RT alone.

Quantified comparisons normalized to GAPDH ( p < 0.0001, ANOVA) show an increase in Csw levels in dfmr1 nulls (1.55 ± 0.13) compared to controls (0.99 ± 0.029), which reveals a highly significant increase in the FXS disease model ( p = 0.0008, Tukey’s, Fig 6C ).

In contrast to the analysis of the first event in the extended follow-up, the number of previous self-harm episodes was highly significant with an increased rate of recurrent self-harm in those with three or more self-harm episodes at baseline (HR 2·05, 95% CI: 1·35, 3·12, p-value=0·0008) and there was a higher rate of self-harm in those referred via hospital (HR 1·64, 95% CI 1·04, 2·61, p -value=0·0348). 3.6.

When gender, VABS II and DBC were entered as covariates, we obtained a highly significant model of the SCQ score ( R 2 = 0.60, F = 8.8, p = 0.0008).

The model was found to be highly significant ( p = 0.0008), with R 2 = 0.9524 and Adj-R 2 = 0.8913, indicating a good fit to the experimental data and good predictive capabilities.

The only highly significant SNPs were seen in Hectd2 ( P = 0.0008, 0.0013 and 0.0022, ANOVA) suggesting that Hectd2 is the most promising candidate in this region.

When categorising based on both signatures, there was a highly significant association with CA9 ( p = 0.0008) and HIF-1α ( p = 0.007) protein expression.

We identified three highly significant module-trait correlations (|AverageCorr | > 0.5, p -value < 8e-4), with each linked to DLB and Control, and composed of CpGs ranging from 39 to 157 (Supplementary Data 2 ).

A highly significant difference was observed between the maximum stress value for the RC scaffolds versus XYP scaffolds when the deposition time was 45 min ( p = 0.0008, F = 81.55, and critical F = 7.71); however, no significant difference was observed for the elongation at break ( p = 0.24, F = 1.89, and critical F = 7.71).

The distribution of hypermethylation and hypomethylation loci among comparison pairs was highly significant (χ 2 (2-df) = 14.17, P = 0.0008).

A positive trend of increased truncations in CSF with increased truncations in plasma was observed, with Pearson correlation coefficients of r = 0.419 ( P = 0.0008) for truncated apoC-I, and r = 0.525 ( P < 0.0001) for truncated apoC-II.

Its addition to a model with T and N stage was highly significant (p = 0.0008, likelihood ratio test).

The NaOCl solution caused a highly significant reduction in post-operative discomfort ( p = 0.0010 day 3; p = 0.0007 day 7) and early painful failures ( p = 0.0008) compared with the control.