Barely Significant

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highly significantp <0.0010.0× alphaqualifiedgold
The criterion of evaluating statistical significance between the experimental and control groups was as follows: p value<0.05 was considered significant and marked as *, p <0.01 as highly significant and marked as **, p <0.001 was very highly significant and marked as ***.
highly significantp < 0.0010.0× alphaqualifiedgold
Intragroup comparisons revealed significant improvement in the control group ( p = 0.024) and a highly significant improvement in the treatment group ( p < 0.001), indicating that the combined regimen achieved a more pronounced and clinically meaningful effect ( Table 2 ) 3.3 Survival analysis During the 6-month follow-up period, survival rates showed a gradual decline in both groups; however, the treatment group consistently demonstrated significantly higher survival rates than the control group at all predefined assessment time points (30, 90, and 180 days).
a significant trendp < 0.0010.0× alphagold
The ES-J also differentiated healthy respondents (i.e., those with no history of MDE and without psychological distress) from subjects with a history of MDE and moderate to severe symptoms of psychological distress ( p < 0.001). The Jonckheere trend test revealed a significant trend ( p < 0.001): a healthy population without history scored higher on ES-J, and a severely distressed population with history scored lower on ES-J.
an increasing trendP <0.0010.0× alphagold
Group 2 (abnormal at 0h, but normal at 1h and 2h), Group 3 (normal at 0h, but abnormal at 1h or 2h), and Group 4 (abnormal at 0h, 1h or 2h) showed an increasing trend in APO risk compared to Group 1 (normal at three time points), with adjusted OR of 1.14, 1.18, and 1.42, respectively ( P <0.001).
extremely significantP < 0.0010.0× alphaqualified
japonensis exhibited an extremely significant ( P < 0.001) positive correlation with the following gut microbiota taxa: Epulopiscium , U114 , Bacteroides , Clostridium and Peptostreptococcaceae (0.8< r < 0.9); and a significant ( P < 0.05) correlation with Enterobacteriaceae , Micrococcaceae , Rummeliibacillus , Lysinibacillus boronitolerans , Veillonellaceae , Oxalobacteraceae , Aeromonadaceae (negative), Marinibacillus and Chitinilyticum (0.4< r < 0.7).