After multivariable adjustment, daily soft drink consumption significantly increased mortality risk in people with CHD and almost reached significance in those without CHD (adjusted hazard ratio (aHR) [95% CI]: 6.09 [2.40–15.48], p < 0.001, and 1.58 [0.97–2.56], p = 0.066 respectively).
The regression model was highly significant [F (4, 2994) = 941.17, p < 0.001] with an Adjusted R 2 of 0.56 ( Table 4 ).
When compared to the control group, it was highly significant (P < 0.001).
Analysis of variance (ANOVA) results indicated a statistically highly significant ( p < 0.001) interaction between year, sowing date and variety.
Our analysis revealed highly significant associations ( p < 0.001) among the accessed root vigour traits (Fig. 3 a).
Highly significant positive correlations were observed between serum GDF-15 and markers of glomerular filtration: serum creatinine ( R = 0.57; p < 0.001) and serum cystatin C ( R = 0.70; p < 0.001; Figure 4(b) ).
The survival of EP patients was better than EPC patients but did not reach statistical significance and, in the Cox multivariate analysis only age had statistically significant effect (HR 1.061, 95% CI 1.026–1.099, p < 0.001).
However, the difference between these two conditions was highly significant, as indicated by high the between-group variance component Q (1) = 13.76, p < .001.
The interaction effects showed that all pairwise interactions between the factors were significant: the interaction between participant group and occlusion was significant F(2,118) = 3.910, p = 0.023,η 2 p = 0.062 ; the interaction between group and emotion was marginally significant F(2,118) = 2.923, p = 0.058,η 2 p = 0.047; and the interaction between occlusion and emotion was highly significant F(4,236) = 86.601, p < 0.001,η 2 p = 0.595.
Finally, in vivo studies of the most active compound 3c against Streptozotocin induced male albino Wistar rats revealed that its administration in the rats for about 4 weeks lead to a highly significant (P < 0.001) decrease in the fasting blood glucose (FBG) compared to the untreated diabetic rats.
AA diameter had a modest but statistically highly significant correlation with the aortic root (Pearson R = 0.30, p < 0.001) and ascending aortic diameter (Pearson R = 0.31, p < 0.001).
Metastatic Sites All phase 2 or 3 clinical trials showed a significant trend over time ( P = 0.001) of increasing proportions of patients with non-osseous metastasis (lymph node, visceral, and soft tissue) (1.4% per year increase), with stable proportion of liver involvement [ 22 ].
Religious affiliation showed a highly significant difference (p < 0.001).
By all data collected, a slight positive—but highly significant—correlation ( p < 0.001) was found between the parameters DON and fungal DNA detected in kernels.
For the 2x2 ANCOVA model addressing differential effects during the two stimulation blocks, the baseline covariate was highly significant, F (1,25) = 100.95, p <.001, η p 2 = 0.80.
While the overall sample size provided sufficient statistical power for primary analyses (highly significant p-values < 0.001), gender-specific subgroup analyses (male: N = 673; female: N = 575) may have limited power to detect smaller effect sizes or subtle gender differences.
The immediate reductions in transmissibility accounting for the effect of PHSMs were highly significant (p values <0·001) and with estimated reductions ranging from 17% (95% CI 13 to 21) to 41% (35 to 46) across the locations and countries, with comparatively higher reductions for Hong Kong and Italy, for which the COVID-19 PHSMs were implemented just before or around the expected seasonal peak ( figure 2 , table , appendix 1 p 21 ).
The mean value among the groups showed a very highly significant difference ( P < 0.001) as shown in Table 2 .
Similarly, the mean values of BD counts also reduced from 77.05 to 59.27 after consumption of NPC, which was found to be highly significant with a P = 0.001.
There were highly significant differences ( p < 0.001) between the sub‐themes in all five prioritized themes.
There was a significant trend for higher CD3 + and γδ IEL densities in higher degrees of morphological damage (Marsh–Oberhuber types 3a-3c) ( p = 0.001 by ANOVA, Fig. 4 ).
We also found a highly significant difference ( p < 0.001 to p < 0.0001; two-tailed Kolmogorov-Smirnov [K-S] test) between the mean radial CT positions of the five largest chromosomes (HSAs 1–5) and those of smaller chromosomes (HSAs 11–22 and Y).
As for AURKA, the differences in protein expression levels of BUB1B in the different histological subtypes of TGCTs were highly significant ( P <0.001).
Using HOMER’s default parameters, the final number of nominally significant ( p value ≤ 0.001) interactions was 41,833 for the healthy dataset and 357,749 for the PANC-1 dataset.
There was a significant operator effect on mean body shape, with all pairwise tests displaying highly significant differences between operators ( P -value <0.001 for all comparisons; Table 1 ), supporting the exploratory between-group PCA ( Fig. 2 ).