“a borderline significant trend”

While cumulative glucocorticoid dose was not consistently associated with cataract risk, higher cumulative exposure showed a borderline significant trend toward increased risk (adjusted OR=1.14, 95% CI 0.99 to 1.31).

Similar results are shown for BMI among postmenopausal women and parous women, although in both cases we found a borderline significant trend for risk association with non-screen-detected breast cancers.

Indeed, only HBB gene showed a borderline significant trend (FDR = 0.08, fold change = 1.2).

The main findings were consistent in sensitivity analyses weighting for nonresponse, and a borderline significant trend for baseline website engagement was significantly associated with reduction in any behavioral health service use when weighting for nonresponse.

Risk reached 3.5-fold for ⩾5 cycles (2 cases, 4 controls, 95% CI 0.4–32.4), with a borderline significant trend ( P -trend=0.057).

Although genetic polymorphisms of the SOC pathway ( STIM1 and ORAI1 ) are not significantly associated with HCC progression after multiple correction, three SNPs of STIM1 (rs6578418, rs11030472, and rs7116520) and one SNP of ORAI1 (rs6486795) showed a borderline significant trend that should be particularly focused on in future studies.

The TAQ haplotype showed a borderline significant trend with reduced heart disease and mortality during follow-up.

For admission with heart failure, group 2 was associated with a lower risk than group 1; however, group 3 did not show a significant difference compared to group 1, while group 4 showed only a borderline significant trend toward a lower risk of admission for heart failure compared to group 1.

The results for the calculated intake of LCn-3PUFA from food reflected the results for seafood intake, while LCn-3PUFA from supplements was not associated with the outcome, with the exception of a borderline significant trend for early preterm delivery.

Older women who cared for a person with dementia and who had more metabolic syndrome indicators showed a borderline significant trend toward more decline in walking speed.

In contrast, no significant association was observed between rs652438 genotypes and asthma susceptibility in individuals older than 40 years (all p > 0.05), despite a borderline significant trend analysis ( p for trend = 0.0487).

Similarly, there was a borderline significant trend for a correlation of FC with the few cases of diarrhea reported in this population at the time of assessment.

The relationship between age at menarche and pancreatic cancer risk using categorized variables rendered a borderline significant trend toward an increased risk with higher categories of age at menarche in the age‐adjusted as well as in the fully adjusted analysis ( p trend = 0.055 and 0.050, respectively), however, when adjusting also for total years of menstruation this association was no longer significant ( p trend = 0.139).

There was a borderline significant trend of increased kidney cancer risk with increasing cumulative exposure to PAHs.

Among them, coping and stress management showed a borderline significant trend between groups at T1, and it became better at T2.

For meat products, a borderline significant trend with increased risk of rectal tumours harbouring G>A transitions was observed (RR for highest vs lowest quartile of intake 2.37, 95% CI 0.75–7.51; P trend 0.07).

Similarly, both studies demonstrated no significant changes in wheeze and other self-reported symptoms, although there was a borderline significant trend towards a decrease of wheeze in our study.

Univariate Cox regression combined with BH-FDR correction revealed a borderline significant trend (FDR = 0.10–0.20, Supplementary Table S4 ) between DDX23 expression and poor prognosis in seven cancer types including LAML, BRCA, LIHC and ACC, with all HRs > 1, suggesting a consistent association.

Additionally, a borderline significant trend indicated an increased number of DED symptoms in the BAK ‐preserved AT group compared to preservative‐free AT users.

The discrepancy between the results of these two systematic reviews is likely a consequence of broader inclusion criteria as Zeiler and colleagues included pediatric studies [ 117 , 118 ], one study that demonstrated a borderline significant trend between CSF-IL-1β and outcome [ 119 ], as well as one study predominantly describing increased CSF levels of IL-1β without a clear relationship to outcome [ 120 ].

Intriguingly, the GEO cohort showed a borderline significant trend toward higher FOXP3/IL-17A ratios in MYC-high patients, potentially indicating a biologically relevant trend of MYC expression and Treg/Th17 balance, consistent with our primary findings.

In contrast, the minimal adherence cluster of 10 participants showed a borderline significant trend toward improved 6-MWD, contrary to our expectations.

, reported a borderline significant trend, where children were more likely to meet their recommended daily dairy products intake if they reported that their mothers drank milk every day (OR = 8·56; 95 % CI (0·96, 76·25); P = 0·05) ( 47 ) .

For OS, the pooled HR was 0.88 (95% CI: 0.78–1.00, p = 0.06), reflecting a borderline significant trend favoring ADCs, with negligible heterogeneity ( I 2 = 0%).

Here we showed a borderline significant trend of ALDH1A1+ phenotype for PFS.