“a decreasing trend”

In the CG, only the BB of both sides showed an increasing trend, while the other muscles remained the same or with a decreasing trend; thus, the difference among the muscles remained highly significant ( p < 0.01) after the intervention, with the consequent slight decrease in total activity (g = 0.01) previously mentioned. 2.2.

Under the – 4 °C treatment, DsCREBBP expression remained at a decreasing trend within 6 days ( P < 0.01), whereas the decrease was highly significant by day 9 ( P < 0.01) (Fig. 3 A).

The expression of ROS in the NMN-treated group showed a decreasing trend at 24 h or 48 h (120.3±15.28 24 h aged vs. 78.00±3.61 24 h aged+NMN; 167.3±5.51 48 h aged vs. 117.0±6.11 48 h aged+NMN; Fig 2B ; p<0.01; n = 3).

Post hoc tests showed a significant decrease in CLO-65 in F1 compared to CLO-0 and a decreasing trend in CLO-65 in F2 compared to CLO-0 ( P <0.01; P =0.086).

General hospitals had the highest proportion (54.8%), while tertiary general hospitals demonstrated a decreasing trend ( p <0.01).

The log-rank trend test indicated that there is a decreasing trend on the rate of 24-h mortality from WBR1 to WBR4 ( P < 0.01).

There was a slight increasing tendency in DDDc of Dasatinib in tertiary hospitals ( p < 0.01), and a decreasing trend in DDDc of Nilotinib in primary hospitals ( p < 0.01).

Conversely, the protein levels of NLRP3 were elevated in the mod group compared to the sham group ( P < 0.01) and downregulated in the Brt-L, Brt-M, and Brt-H groups in a decreasing trend compared to the mod group (Fig. 4 E, P < 0.01).

The contents of polysaccharide in F, S and P were 398.60 mg/g, 354.20 mg/g and 316.47 mg/g, respectively, as illustrated in Figure 2 a, indicating a decreasing trend with a significant difference ( p < 0.01).

Over a 48-month follow-up period, all three groups showed a decreasing trend in knee JSW, with the IACI group having the fastest JSW decline rate at -0.020 mm/month (95% CI: -0.027 to -0.013, p < 0.01).

The results showed that, compared with the LPS + sh-PTEN group, the LPS + sh-PTEN+Rapa group had significantly decreased SOD levels and significantly increased MDA levels ( P < 0.01), while the LPS + sh-PTEN + 3-MA group showed an increasing trend in SOD levels and a decreasing trend in MDA levels ( P < 0.01, Fig. 5 E).

In 2009, 2012 and 2018, the average number of drugs per prescription was 3.66, 3.29 and 2.77, respectively, the percentage of prescriptions including antibiotics was 65.40%, 62.31% and 46.00%, respectively, and the percentage of prescriptions including injections was 55.75%, 49.66% and 37.48%, respectively, all of which showed a decreasing trend (p<0.01).

Both single infection and multiple infection exhibited a decreasing trend, with the AAPC for multiple infections (AAPC = −13.9%, p = .010) being higher than that for single infections (AAPC = −8.1%, p = .029) ( Figure 3 ).

Furthermore, the levels of SNRPD1 in each group showed a decreasing trend with the increase in treatment time ( P < 0.01) ( Figure 2G ).

Moreover, an immunofluorescence staining assay revealed a decreasing trend in the proportion of slow myofibers and an increase in fast myofibers in mice treated with BBE ( p < 0.01 for BBE50 and BBE100 in slow and fast myofibers) ( Figure 4 E,F).

There was an increasing trend of having missing teeth ( p = 0.03) as people aged and a decreasing trend in the number of filled teeth ( p < 0.01).

After the implementation of the NVBP policy, the continuously increasing trend of the average monthly per-visit expenditure of chemotherapy drugs ( p < 0.01), oral endocrine drugs ( p < 0.01) and TCM ( p < 0.01) has been effectively mitigated; in particular, the average monthly per-visit expenditure of TCM has been changed from an increasing trend to a decreasing trend with 12.22 CNY ( p < 0.01) per month.

We observed a decreasing trend in urinary concentrations of CPPDQ ( r s = 0.69, p < 0.01) and 6PPDQ ( r s = 0.74, p < 0.01) with increasing age.

The ASR of YLD and DALY showed an increasing trend from 1990 to 2021 ( P < 0.01), but the ASR of mortality and YLL showed a decreasing trend ( P < 0.01).

The abundance of Lactobacillus and Helicobacter increased significantly in the SAP group compared with the SO group ( p < 0.05), and they showed a decreasing trend in the Q and E groups compared with the SAP group, with the abundance of Lactobacillus decreasing significantly in the Q group ( p < 0.01).

Compared with the LPS group, the lung index of the OS and DXM groups showed a decreasing trend ( P <0.01), while the lung index of the OS and DXM groups also showed an increase compared with the NS group (P <0.05).

There was a decreasing trend in weight in the experimental group across the three time points (baseline to the second assessment), as compared to the control group (F = 4.29, P = .01).

A decreasing trend was also observed in the Fer-1-treated group ( P < 0.01) ( Figure 7B ).

During the same period, there was a decreasing trend in the age-adjusted prevalence rate of poor diet [primary American Heart Association (AHA) score <20; 47.5% (37.9%–57.0%) to 37.5% (25.7%–49.3%), p < 0.01].

The first sampling time showed a very high standard error due to the variability between replicates, but afterwards, clearance rates stabilized at around 50 mL h −1 gDW −1 , showing a decreasing trend from the beginning ( p < 0.01).