Barely Significant
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“a favorable trend”

1,336 sentences · 1,336 papers · 2,253 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Unsurprisingly, in the overall cohort of 255 patients, no statistically significant differences were observed in disease-free survival (DFS) (HR 0.71, 95% CI 0.48–1.05, p = 0.084) or overall survival (OS) (HR 0.69, 95% CI 0.48–1.05, p = 0.096), although a favorable trend was noted in the surgical arm, suggesting the possibility of a type II error.
did not reach statistical significancep = 0.0511.0× alphaplainly factual
MFC-MRD–free survival showed a favorable trend in the maintenance group, although this did not reach statistical significance (2-year MFC-MRD–free survival: 85.5% [95% CI, 74.4–98.3] vs. 68.7% [95% CI, 57.3–82.4], p = 0.051).
The WIZARD (Weekly Intervention with Zithromax for Atherosclerosis and its Related Disorders) study failed to find a long-term benefit, even though a favorable trend was noted during and shortly after 3 months of azithromycin treatment. 12 More recent trials, ACES (Azithromycin and Coronary Events Study) 13 and PROVE IT-TIMI 22 (Pravastatin Or Atorvastatin Evaluation and Infection Therapy), 14 also reported a negative outcome.
Updated results after 40 months of follow-up showed a favorable trend in terms of OS for capivasertib plus paclitaxel, regardless of the PIK3CA/AKT/PTEN mutational status (median OS in the overall population 19.1 months vs. 13.5 months; HR 0.7; 95% CI: 0.47–1.05; p = 0.085) ( Schmid et al., 2021a ).