“a marked trend”

As text quality improves, AI content shows a marked trend toward reduced colloquialism and increased clarity, logical coherence, and linguistic formality.

The strong presence of twitter (75; 464), sentiment analysis (43; 221), text mining, and machine learning reveals a marked trend toward computational methodologies to analyze digital discourses, social interactions, and conspiracy narratives related to vaccines.

Introduction With economic development, accompanied by shifts in dietary patterns and the adoption of sedentary lifestyles [ 1 ], the global prevalence of obesity has exhibited a marked trend of getting higher and younger.

Notably, higher nuclear YAP1/TAZ expression correlated with patient age and showed a marked trend toward association with extrapleural tumour location.

On the social novelty trial, baseline (pretreatment) social novelty index scores revealed a marked trend toward a social familiarity preference in the aged group, confirming the pattern observed in Experiment 1 ( Fig. 6 A ). iTBS had no effect on social novelty in either the young or aged group overall and, moreover, no effect on the aged rats when the results were stratified by memory status, documented in the water maze (Extended Data Fig. 5-1 C , D ). 10.1523/ENEURO.0422-25.2025.f5-1 Fig 5-1 Effects of sham and TMS treatment on sociability and social novelty index scores in aged rats subgrouped according to hippocampal memory in the water maze.

Matrix metalloproteinases MMP-2 and MMP-3—critical enzymes involved in extracellular matrix degradation—were detectable in both groups, with a marked trend toward higher concentrations in ACS obtained from OA patients ( Figure 2 m,n).

Furthermore, a marked trend of increased Smad7 expression was found in HFD-P compared to CT-P mice ( Figure 7 E).

As can be observed from the figure, with the increase in HBR, there is a marked trend of decreasing alarm time across all monitoring points.

A marked trend toward increased PD-1 expression in the CD3 + /CD4 – compartment (presumed CD8 compartment) was also noted in irradiated versus nonirradiated tumors ( Supplemental Figure 5B ).

Likewise, no significant differences were observed between groups in the use of lipid-lowering or antihypertensive medications at baseline (Chi-square test: P = .112 and P = .059, respectively), despite a marked trend of use of such medication among the participants with obesity.

Compared with the 2010 measurement by Warner et al.,(2013)—when the water table stood at about 12.00 m 37 with a mean electrical conductivity of 2 376 μS/cm and mean TDS of 1 751 mg/L—the 2022 survey reveals a marked trend toward both drawdown and salinization: the average depth has increased to 19.39 m, mean EC has risen to 4 590 μS/cm (an increase of 93%), and mean TDS has climbed to 4.31 g/L (an increase of 146%).

Background Colorectal cancer (CRC) is one of the most common causes of cancer-associated death worldwide, and a rapid increase in the incidence and mortality of CRC has been predicted with a marked trend in the younger age group.

Reactions that use either indazole boronic acid 2a or boronic ester derivative 2b perform significantly better (under the conditions tested), sharing similar reactivity. Irrespective of the choice of the organoboron derivative, there is a marked trend in (pseudo-) haloquinoline choice – the worst performing substrate being 6-Cl-Q 1a , with its strong carbon-chloride bond (oxidative addition being more challenging , ).

Table 2 shows that the modularity index of the GIOTN underwent phased changes from 2000 to 2023: it rose gradually from 0.30 in 2000–2006 to 0.49, indicating strengthened intra‐community ties and weakened inter‐community links, with early signs of regional clustering; declined progressively to 0.06 in 2006–2014, reflecting enhanced inter‐community connectivity and greater trade network integration; peaked at 0.50 in 2015, when the network split into multiple highly autonomous trade communities, underscoring a marked trend toward regional cooperation; fell back to 0.08 in 2015–2020 as inter‐community links intensified and the network reintegrated, demonstrating the resilience of globalization; and rose again in 2021–2023, signaling stronger intra‐regional cluster connectivity in the post‐pandemic era and the reemergence of regional cooperation as a dominant feature.

In contrast to these trends for a fairly small effect of zero tillage on SOC there is a body of evidence, mainly from Brazil, showing a marked trend for zero tillage to be effective at preserving SOC after clearance of native Cerrado vegetation growing in highly weathered oxisol soils in tropical environments.

Following EA intervention for 4 weeks, the HFD + EA group showed a marked trend in weight loss ( Figures 1A, B ).

Participants 3 and 4 had a marked trend for their average post-transit Speed scores to be slower in comparison to their pre-scores.

A marked trend for improved recovery in both tests was detected in the rats in the WBV14 group.

In U251 cells, the effect of PP2 on invasiveness was not significant; however, there was a marked trend towards a decrease in invasion ( Fig. 3B ).

For the numbers of uncomplicated appendicitis there is a marked trend toward a lower number during the pandemic period compared with the pre-pandemic period in most studies.

On the other hand, there was a marked trend among patients with low circulating CXCL14 levels to have worse outcomes (composite outcome and ACM) when compared with those with higher circulating CXCL14 levels ( Figure 5 and Table 3 ).

This increase showed a marked trend in types such as ostomy, hearing, and physical disabilities.

Introduction Closed reduction (CR) is one of the most common procedures for treating late-detected developmental dislocation of the hips (DDH) ( 1 ), considering a marked trend toward spontaneous improvement of the hips after reduction ( 2 - 4 ).

With the aid of solid-state SQUID magnetometry, we observed a marked trend of lesser antiferromagnetic coupling when expanding substitution to the heavier chalcogenide congeners which we attribute to the ∠Fe–E–Fe angle becoming more acute due to decreased hybridization in the heavier chalcogenides and poorer orbital overlap with Fe II d-orbitals.

Overall, there was a marked trend toward using various TEET options after 2017.