Figure 7B shows that RAB15 was significantly positively correlated with aDCs and macrophages, and showed a near-significant trend with cDCs.
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The exposure of endothelial cells to monodansylcadaverine did not reduce the uptake rate of ApoExos or ApoBodies but did reduced transferrin, a protein known to enter cells through clathrin-dependent endocytosis, and ExoN to a near-significant trend (Fig. 3A ).
Additionally, a mediation analysis conducted on age-matched subgroups also indicated a near-significant trend in the mediating role of the CSVD total score between age and striatal iron deposition, further details can be found in Supplementary Table S4 and Fig. 1 .
Significant differences were declared at p ≤ 0.05, while p values between 0.05 and 0.10 were considered a near-significant trend.
Yet higher BIS was linked to a more negative memory bias (ambivalent CSs more often recalled as paired with negative USs), and there was a near-significant trend whereby more positive (versus negative) recall of ambivalent pairings predicted more positive (versus negative) CS ratings.
Moreover, a near-significant trend was found between KLs at admission and hospital LOS (H LOS), with a Kruskal–Wallis statistic (H) of 11.87 and a p -value of 0.079, suggesting that patients with more extreme potassium imbalances at admission may experience longer hospitalizations.
Our data corroborate these earlier notions since several citrullinated peptides emerged as useful variables, as well as MCP-1 demonstrating a near-significant trend of being elevated in responders.
A T-probability of p ≤ 0.05 was considered statistically significant, while 0.05 < p ≤ 0.10 indicated a near-significant trend.
Within-group ANOVA analysis (F = 2.78, p = 0.089) approached but did not achieve statistical significance ( p > 0.05), suggesting a near-significant trend but no definitive time-dependent effect.
There was a near-significant trend observed in the relationship between COVID-19 severity and QTc prolongation, with patients who experienced moderate to severe COVID-19 course (median QTc 430 ms) compared to those with mild disease (median QTc 400 ms) ( p = 0.054).
P < 0.05 was considered to be statistically significant, whereas 0.05 ≤ P < 0.10 was considered to be a near-significant trend. 3.
Self-evaluation (“bad feeling about yourself”) showed significant linearity only with PSYRATS-AH classification and a near-significant trend with HPSVQ classification.
Significance was determined at p < 0.05; p < 0.1 was taken to indicate a near-significant trend. 3.
In contrast, expression of heme oxygenase-1 (HO-1), another target gene of Nrf2 ( 69 ), was found to correlate with thyroid cancer aggressiveness (stage and risk of recurrence, plus a near-significant trend for extra-thyroidal invasion), but not with tumor size or lymph node metastasis ( 70 ).
Values of p ≤ 0.05 were considered statistically significant and 0.05 < p ≤ 0.10 values were considered to present a near-significant trend. 3.
Notably, PC2 showed a near-significant trend in distinguishing children with ADHD from neurotypical controls.
In response to compound 1 treatment, in addition to the above-mentioned CD8 + T cell expansion, we observed an increased frequency of NK cells in a near-significant trend (Figure 2 D, clus_3, blue vs. black) and a decreased frequency of pro-tumorigenic M2-like macrophages 41 (clus_8, blue vs. black), which supports tumor suppression due to compound 1 treatment.
In plasma, MDA levels were marginally higher in leukemia children compared to controls (F = 3.33, p = 0.072, η 2 p = 0.044), suggesting a near-significant trend at the 10% level.
A probability of 0.05 < P < 0.10 was considered a near-significant trend. 3.
However, one EIM (sICAM1) and two CCs (SCD40L and IL1RA) showed a near-significant trend of elevation in high severity (Fig. 2 A).
The OCD group had significantly lower TEPS-consummatory pleasure (CON) scores than HCs, reflecting greater consummatory anhedonia severity in OCD, but only a near-significant trend toward a difference in TEPS-anticipatory pleasure (ANT) scores.
Specifically, the index patient judged the most ambiguous faces (at the 50% fear intensity level) as fearful at a significantly higher rate than the control group ( p = 0.03), and showed a near-significant trend toward heightened fear judgments for faces with moderate fearful expressions (60% level).
Differences were regarded as significant at p ≤ 0.05, while 0.05 < p ≤ 0.10 was considered a near-significant trend.
The type of atrial fibrillation (AF) was incorporated as it demonstrated a near-significant trend and constitutes a key determinant in both the pathophysiological profile and interventional strategy for AF ablation.
Significance was declared at p (probability) < 0.05, and 0.05 ≤ p < 0.10 was considered a near-significant trend. 3.