Second, a numerical trend toward a higher prevalence of asymptomatic grade 1 pneumonitis at diagnosis was observed in patients with lung cancer than in those with non-lung cancers (61.9% vs 50.0%), possibly reflecting surveillance intensity variations rather than biological differences, as individuals with lung cancer typically undergo more frequent chest CT imaging for tumor response assessment.
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In remaining subgroups, CAP score reduction at 6 months showed a numerical trend favouring EPL versus placebo (Figure S2E ).
Analysis of mean ASSR amplitudes did not reveal a statistically significant main effect of attention, although a numerical trend toward larger responses during left-ear attention was observed ( Figure 4 ).
When biomarker levels were examined according to severity, a numerical trend toward lower values in severe cases was observed for the TOC, NOx, catalase, and thiols.
These findings indicate that CD276 is the primary diagnostic biomarker, with the combined panel showing a numerical trend toward improvement but lacking statistical significance for the incremental benefit of adding DKK3 in this cohort of 40 patients per group.
Exploration of PSA-PFS showed a numerical trend toward longer median PSA-PFS in patients with at-or-above-median steady-state HCQ levels [6.38 months; 95% CI, 2.76–not applicable (NA)] compared with those with below-median levels (3.81 months; 95% CI, 2.70–NA).
When overall survival data are evaluated, a numerical trend toward shorter survival times in the HER3-positive group was observed, consistent with the literature, though statistical significance was not reached.
Although no statistical significance was reached, there was a numerical trend toward higher Ki-67 values in tumors with poorer response: the mean Ki-67 ranged from 12.3 ± 10.0% in stable tumors to 17.8 ± 11.1% in those showing reduction, reaching 20% in progressive cases.
Results showed a significant main effect of speech rate ( F (1,13746)= 2573.8, p <.001), but not of bin or an interaction, indicating that the GloVe-Written summary method does not detect an effect of information position, despite a numerical trend towards a recency effect (Fig. 8 ).
The absence of a statistically significant association with OS, despite a numerical trend, may reflect the influence of additional clinical factors or subsequent lines of therapy that mitigate the long-term impact of TP53 status.
Only one of the included studies reported on the risk of asthma exacerbations and hospitalization due to asthma and found a numerical trend towards increased risk of exacerbations and asthma hospitalization for the asthma and HF group compared to the asthma-only group, though this did not reach statistical significance [ 16 ].
4.1%, P = 0.79) compare favorably with published series [ 33 , 34 ], and the MWA group showed a numerical trend toward lower cement leakage (2.9% vs. 4.1%), though this did not reach statistical significance likely due to our limited sample size.
However, patients in the late era showed a numerical trend toward improved survival outcomes compared to those in the early era.
Within the population with T2DM (N = 180), contrary to our initial hypothesis, metformin treatment showed a numerical trend towards shorter PFS, though this did not reach statistical significance (HR = 1.41, 95% CI [0.97–2.05], p = 0.069).
LEF showed a numerical trend toward favoring in multiple subgroups, including the elderly, patients with comorbidities, and those infected with specific pathogens, particularly in the ECR analysis.
During the MCI to Alzheimer’s disease transition, females exhibited significant GMV reductions in both regions, whereas males showed a numerical trend towards relative stability or mild increase, which was not statistically significant.
Although pooled mortality did not differ significantly between groups, a numerical trend toward higher mortality in letermovir-treated patients was observed in some cohorts.
Microbiological analyses, although based on pooled samples, indicated a numerical trend toward lower thermotolerant coliform counts in NDF-supplemented groups.
Conclusions In aSAH patients undergoing cranioplasty after DC, customized 3-D printed implants achieved significantly better anatomical restoration and showed a numerical trend toward fewer complications compared with autologous bone.
This may explain the nonsignificant difference in GAPP <3, despite a numerical trend.
Although our analysis did not yield statistically significant differences in the distribution of causes of death across NLR groups, a numerical trend was observed, whereby infection-related mortality was higher in the high NLR group, particularly among patients with early mortality.
Notably, the 4GS showed a numerical trend toward higher baseline values in responders, but the difference did not reach statistical significance.
While the NOTUS trial did not achieve statistical significance for mean SGRQ change, it indicated a numerical trend toward improvement.
MAIC results were similar, also suggesting comparable rates of CR (OR 1.12; 95% CI 0.61–2.08) and CR + CRh (OR 0.83; 95% CI 0.46–1.50) between treatments; the adjusted point estimate indicated a numerical trend in favor of olutasidenib for CR and ivosidenib for CR + CRh but was not statistically significant.
This reduces statistical power despite a numerical trend toward higher SI rates with anti-CD20 therapy.