“a numerical trend”

However, when altitude increases to ≥3,500 m, the decreases in SDNN and the increases in LF/HF become significantly greater, whereas RMSSD, pNN50, HF, and LF, despite showing a numerical trend toward “lower values at higher altitude,” do not exhibit statistically significant differences between subgroups.

Although no statistical significance was reached, there was a numerical trend toward higher Ki-67 values in tumors with poorer response: the mean Ki-67 ranged from 12.3 ± 10.0% in stable tumors to 17.8 ± 11.1% in those showing reduction, reaching 20% in progressive cases.

However, a numerical trend of fewer relapses and 24W-CDP events was observed for patients treated with IFN β-1a in the OPERA cohort.

When focusing on behavioral and neural changes related to strategy transition, we first observed post-transition slowing in behavior ( Fig 2F ) and a numerical trend of increased fMRI activation in the prefrontal cortex following estimated transition points ( S4 Fig ).

There was a numerical trend towards earlier diagnosis over time, with stage IIIA NSCLC diagnosed in 33.2% of the 2000–2002 cohort, versus 46.5% of the 2012–2013 cohort.

Results: This study revealed a numerical trend toward higher patient satisfaction with on-site consultations across both age groups, particularly among those aged 18-40, although the difference among patients aged >41 years was minimal; however, these differences were not statistically significant.

Among people with obesity or overweight, a numerical trend of multiple obesity-related complications and higher mean (SD) CCI scores was observed in individuals with higher BMI than in those with lower BMI (CCI scores: normal BMI: 1.3 [1.8]; overweight: 1.1 [1.6]; Class 1 obesity: 1.2 [1.7]; Class 2 obesity: 1.3 [1.7]; and Class 3 obesity: 1.5 [1.8]).

In this post hoc, exploratory evaluation, there appeared to be a numerical trend toward deeper responses in the Q4W cohort, with several patients maintaining tumor shrinkage for an extended period.

Additionally, it was associated with a numerical trend towards fewer postoperative complications and further enhance parental satisfaction with the surgical outcomes.

In a post hoc subgroup analysis of TN patients in the phase III, PHOENIX trial, a numerical trend was observed toward improved EFS and PFS with ibrutinib in combination with R‐CHOP when compared with R-CHOP alone in patients with high MYC/BCL2 co‐expression [ 89 ].

In addition, there was a numerical trend toward lower accuracy for word trials than nonword trials, although this difference did not reach significance.

Although fixed-dose clinical trials did not show a statistically significant treatment effect difference between 75 mg and 225 mg per day, there was a numerical trend suggesting possible superiority of higher doses, which is often seen in clinical practice.

Our data suggest a numerical trend towards decreased cell proliferation (Ki-67 staining) in CRC0076 (which expresses high levels of BCL-2) following ABT-199 treatment ( Figure S5 ). 2.3.

Although stratified analysis showed a numerical trend toward a stronger NOTCH1 m effect in IGHV-mutated patients (HR=3.26 vs. 1.29), the wide confidence intervals and lack of statistical significance preclude definitive conclusions, especially given the low prevalence of NOTCH1 m in this subgroup (n=9 with 3 events).

AS alone resulted in weight loss comparable to sham and TBI alone, whereas the combination of TBI + AS showed a numerical trend toward nearly doubled weight loss compared with single AS or TBI exposure; however, this difference did not reach statistical significance (Fig. 4 A).

Similarly, although none of the treatments demonstrated statistically significant effects, a numerical trend favoring rasagiline, safinamide, and rasagiline ER 0.75 mg over placebo was observed in the analysis of subjective daytime sleepiness measures.

Discussion In this randomised controlled trial, adjunctive silodosin after ESWL did not achieve a statistically significant improvement in the primary endpoint of overall SFR compared with standard care, although a numerical trend towards higher clearance was observed.

Similarly, survival analysis indicated that all three treatment regimens significantly prolonged survival compared with controls, with a numerical trend toward greater survival benefits in the HAIC plus anti-PD-L1 group relative to both systemic treatment groups (Supplementary Fig. 18K ).

Nonetheless, the T-VEC-pembrolizumab group showed a numerical trend toward longer median PFS (14.3 months vs. 8.5 months) and slightly higher ORR (48.6% vs. 41.3%) and DRR(42.2% vs. 34.1%), while maintaining a comparable safety profile [ 74 ].Although the combination of T-VEC and pembrolizumab did not achieve a significant overall survival advantage in the first-line setting for advanced melanoma, it remains under active investigation in PD-1 inhibitor-refractory melanoma and other malignancies.

6 A–F), although a numerical trend of decline from NC to MC followed by partial recovery in RG was observed.

Neurological Recoveries Compared to Comparative Clinical Trials : mRS and NIHSS scores at 90 days post-stroke were not statistically worse than those in comparative historical studies, and at least one of these outcomes showed a numerical trend for improvement in the cooled patients.

We observed a numerical trend towards lower frequency of mild infections in the probiotic group compared to the placebo group (15 vs. 28 during intervention, 6 vs. 11 in the observation period).

Moreover, there was a numerical trend towards more error-prone responses after go trials than cue-only trials (8.6% vs. 7.2%).

While some strategies in our trial, such as mADF and lTRE, showed a numerical trend toward a slightly higher adjusted expenditure, this did not reach statistical significance.

Among the HBeAg-positive patients there was a numerical trend of reduced LTCs between the NA treatment (3.4%, 20/587) and no treatment (12.0%,56/468) (RR:0.24, 95%CI: 0.14-0.40; Figure 7 ).