Barely Significant
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“a numerical trend”

1,013 sentences · 1,013 papers · 1,817 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Subgroup analyses Annualized relapse rate The significant reduction in ARR observed in the overall pooled analysis of the ITT population with ocrelizumab, relative to IFN β-1a (47% [ p < 0.001]), was maintained across the majority of subgroup-levels, including study, region, age, sex, baseline BMI, prior DMT use and prior relapse, baseline EDSS, normalized brain volume, and gadolinium-enhancing T1 lesions; a numerical trend favoring ocrelizumab was observed for the specific subgroup strata of patients aged ≥ 40 years (Fig. 1 ).
Among males, there was a numerical trend towards lower serum testosterone levels in patients harbouring a TA allele, which did not attain statistical significance ( TA/TA : 3.75 ± 2.03 vs T/TA : 4.95 ± 3.62 vs T/T : 5.65 ± 3.02; P = .339; Figure S4). 4 DISCUSSION Recently, a study linking exome sequence data from the DiscovEHR cohort 13 to electronic health records reported, that the HSD17B13 rs72613567 T > TA variant is associated with reduced risks of ALD/NAFLD as well as alcoholic and non‐alcoholic cirrhosis.
While the exploratory analyses were not statistically significant, there was a numerical trend for an impact of ONCOS-102 on survival in chemotherapy-naïve patients (n=17): 30-month OS rate was 34.1% vs 0%, median OS was 20.3 vs 13.5 months ( figure 3C ), and median PFS: 8.9 vs 7.6 months ( figure 3D ) in the ONCOS-102 versus chemotherapy-alone cohorts.
Accordingly, a numerical trend toward higher remission/LDA rates was observed in the RTX-originator group across disease activity indices; however, these differences did not reach statistical significance and likely reflect baseline imbalances in disease severity and prior treatment exposure.
On the other hand, the TOE-group showed a numerical trend towards more deaths. 85 While some studies show greater rates of successful restoration of sinus rhythm with TOE-guided cardioversion, 85 , 86 inconsistent results exist as to long-term maintenance of sinus rhythm. 85 , 89 Key points When no LA thrombus is identified on TOE, cardioversion can be performed safely, provided that sufficient anticoagulation is achieved before TOE.
When reviewing results of the PRISM study in detail, Ig‐pre‐treated patients showed a numerical trend for a higher responder rate than Ig‐naïve patients (84.2% vs 69.6%) possibly reflecting the fact that Ig‐pre‐treated patients were selected for their positive clinical response to IVIg and consequently are more likely to respond again.