“a significant trend”

OxLDL significantly reduced MMP integrity, while NAC treatment restored mitochondrial polarization showing a significant trend with increasing doses ( p < 0.01).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used [ 21 ]; if the trend was not significant Dunnett’s test was used [ 22 ].

Both preoperative imaging and intraoperative exploration revealed a significant trend of increasing lesion diameter across types I, II, and III ( P < 0.01).

However, a significant trend of higher LN count and higher likelihood of liver metastases was observed ( P = 0.010).

At the seasonal level, we found a significant trend in NEE only in autumn, which indicated that the forest's net C sink increased during autumn over the 26 years of the study ( p < 0.01; Table 1 ). 3.2 Trends in Daily NEE Fluxes Over Time To assess the effects of climate change on NEE throughout the study period, we analyzed the days with the strongest net C uptake, that is, 1st, 5th percentiles of NEE c,DOY , and strongest net C loss, that is, 95th and 99th percentiles of NEE c,DOY , as well as the median NEE c,DOY during the 26‐year period (Figure S4 ).

Compared with the latter, our cohort presented increased mutation frequency of DUSP2 , BTG2 , IRF4 , MEF2B , MYC , CD79B , BCL7A , NFKBIE , FAS , and CIITA ( p < 0.05), with a significant trend toward changes in TP53 , CCND3 , CD58 , and CXCR4 ( p < 0.01).

The average changes in ln(UACR) for participants in the 2nd, 3rd, and 4th quartiles relative to the reference quartile were respectively − 0.06, 0.08, and 0.22, presenting a significant trend ( P < 0.01).

There was also a significant trend ( p < 0.01) in prevalence of lower respiratory symptoms that improved when away from the building: 52% of those with postoccupancy-onset asthma, 41% of those with adult preoccupancy-onset asthma, 27% of those with childhood asthma, and 23% of those with no physician-diagnosed asthma ( Table 4 ).

Comparison of the distribution of SCAI Shock stages revealed a significant trend towards a higher proportion of stages D (58.9% vs. 47.2%) and E (1.8% vs. 0.4%) ( P = 0.01) among the 1‐year non‐survivors.

Similarly, there was a significant trend in all item scores (with the exception of environmental autonomy) across the cognitive subgroups (all p<0.01).

Furthermore, the combination group exhibited a significant trend towards reduced all-cause mortality risk relative to the antiplatelet group (aHR 0.11, 95% CI 0.02–0.59, p = 0.010; Figure 5D ). 3.7.3.

There was a significant trend toward higher WFDC2 expression in patients with low PDCD1 expression (p = 0.01).

The results demonstrate a significant trend in pain changes in the exercise group (F (2, 24) = 5.31, P = 0.01, η 2 = 0.31), while it is not significant in the control group (F (2, 30) = 0.57, P = 0.57, η 2 = 0.04).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used ( Williams, 1986 ); if the trend was not significant, Dunnett’s test was used ( Dunnett, 1955 ).

Multivariable analysis revealed a significant trend of low GCS ( p < 0.01), age over 80 years ( p < 0.01), DC ( p < 0.01), EVD placement ( p < 0.01), tracheotomy ( p < 0.01), and hypertension ( p < 0.01) After repeated operations (OR 2.199), tracheotomy (OR 7.219) can be used to predict the unfavorable outcomes strongly and independently.

With respect to transcendent orientation, the mean score was higher in women ( P = 0.03) and in those working < 30 h/week ( P = 0.03); a significant trend also emerged in the mean COPE-NIV-25 score, which increased with age ( P = 0.01) and length of employment ( P = 0.01).

Conversely, in the population of patients with sperm abnormality, we found a significant trend increase from day 1 to day 7 of TSC (16.38 vs. 56.0; p<0.01), sperm concentration (million/ml) (8.0 vs. 18.0; p<0.01) and morphology (3.0 vs. 5.0; p<0.01).

There was also a significant trend between higher waist circumference and the odds of elevated SII (p=0.01), and PLR (p<0.0001).

The improved parameter calculation and automated and objective quality assessment resulted in a significant trend ( p < 0.01) when applying the tolerant quality criteria, which translates into a NMCdi decrease of 4.3 percentage point (pp) per cmH 2 O of PEEP relative to a PEEP of 3 cmH 2 O.

A significant trend of higher summed costs (indirect costs to caregivers, costs to employers, intangible costs to patients and caregivers) in more severe AD was observed ( p < 0.01).

However, among kidney transplant patients younger than 50 years at the time of transplantation ( n = 754), there was a significant trend for increasing the occurrence of post-transplant CV complications along the consecutive KDRI quartiles (χ 2 = 7.3; p < 0.01), with the frequency of CVEs across the study groups as follows: Q1 13/205, Q2 23/179, Q3 24/166, and Q4 21/123.

Gestational week at examination, LDL-C, HDL-C, and GWG showed a significant trend of first increasing and then decreasing with the TyG index ( P < 0.01).

Regression analysis indicated a significant trend ( P =.01) increase in app release, with a 2.40 unit increase per year before 2020 and a 7.01 unit decrease after, showing a post-2020 decline of 4.61 units per year.

Based on the biomarker values related to serum L-fucose levels in this study, a significant trend (P < 0.01) was observed with the progression of OSMF (C) ( Table 2 ).

Compared to Q1, the Q2 and Q4 groups showed significantly reduced risk in 1-year stroke recurrence (Q2: HR = 0.46, 95% CI 0.27 to 0.79, P = 0.005; Q4: HR = 0.47, 95% CI 0.27 to 0.81, P = 0.007), with a significant trend across all quartiles ( P = 0.01 for trend tests).