“a significant trend”

There was a significant trend toward higher WFDC2 expression in patients with low PDCD1 expression (p = 0.01).

Plasma NGAL levels also increased progressively with AKI stage: 481.6 ng/mL (stage 1), 625.5 ng/mL (stage 2), and 760.2 ng/mL (stage 3), showing a significant trend ( P < 0.01).

With respect to transcendent orientation, the mean score was higher in women ( P = 0.03) and in those working < 30 h/week ( P = 0.03); a significant trend also emerged in the mean COPE-NIV-25 score, which increased with age ( P = 0.01) and length of employment ( P = 0.01).

However, a significant trend of higher LN count and higher likelihood of liver metastases was observed ( P = 0.010).

There was a significant trend for White patients to be more readily offered CAR-T than their non-White counterparts (offered CAR-T: 29% vs 6%; P <0.01), with BsAbs also more likely offered to White patients (offered BsAbs: 21% vs 8%; P =0.096).

At the seasonal level, we found a significant trend in NEE only in autumn, which indicated that the forest's net C sink increased during autumn over the 26 years of the study ( p < 0.01; Table 1 ). 3.2 Trends in Daily NEE Fluxes Over Time To assess the effects of climate change on NEE throughout the study period, we analyzed the days with the strongest net C uptake, that is, 1st, 5th percentiles of NEE c,DOY , and strongest net C loss, that is, 95th and 99th percentiles of NEE c,DOY , as well as the median NEE c,DOY during the 26‐year period (Figure S4 ).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used [ 21 ]; if the trend was not significant Dunnett’s test was used [ 22 ].

Multivariable analysis revealed a significant trend of low GCS ( p < 0.01), age over 80 years ( p < 0.01), DC ( p < 0.01), EVD placement ( p < 0.01), tracheotomy ( p < 0.01), and hypertension ( p < 0.01) After repeated operations (OR 2.199), tracheotomy (OR 7.219) can be used to predict the unfavorable outcomes strongly and independently.

The results demonstrate a significant trend in pain changes in the exercise group (F (2, 24) = 5.31, P = 0.01, η 2 = 0.31), while it is not significant in the control group (F (2, 30) = 0.57, P = 0.57, η 2 = 0.04).

The fully adjusted model demonstrated a significant trend correlating increased TTHC (P<0.01 for trend), SR (P<0.001 for trend), and Ki-67 expression (P=0.004 for trend) with ALNM.

1 A) revealed a significant trend for all-cause mortality among GOLD stages ( P < 0.01 for trend).

The improved parameter calculation and automated and objective quality assessment resulted in a significant trend ( p < 0.01) when applying the tolerant quality criteria, which translates into a NMCdi decrease of 4.3 percentage point (pp) per cmH 2 O of PEEP relative to a PEEP of 3 cmH 2 O.

Similarly, there was a significant trend in all item scores (with the exception of environmental autonomy) across the cognitive subgroups (all p<0.01).

A significant trend of higher summed costs (indirect costs to caregivers, costs to employers, intangible costs to patients and caregivers) in more severe AD was observed ( p < 0.01).

There was also a significant trend between higher waist circumference and the odds of elevated SII (p=0.01), and PLR (p<0.0001).

Both preoperative imaging and intraoperative exploration revealed a significant trend of increasing lesion diameter across types I, II, and III ( P < 0.01).

Gestational week at examination, LDL-C, HDL-C, and GWG showed a significant trend of first increasing and then decreasing with the TyG index ( P < 0.01).

Compared with the latter, our cohort presented increased mutation frequency of DUSP2 , BTG2 , IRF4 , MEF2B , MYC , CD79B , BCL7A , NFKBIE , FAS , and CIITA ( p < 0.05), with a significant trend toward changes in TP53 , CCND3 , CD58 , and CXCR4 ( p < 0.01).

However, a significant trend was noted where the proportion of individuals with high LDL-PRS increased with rising LDL-indicating a polygenic component at play ( p = 0.01) (Supplementary Fig. 2).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used ( Williams, 1986 ); if the trend was not significant, Dunnett’s test was used ( Dunnett, 1955 ).

After LPS stimulation, the macrophage supernatant co-cultured MSCs in the hydrogel groups showed a significant trend of ALP formation, among which the bone activity of the hydrogel containing TA@Ag NPs was the most significant ( Fig. 4 c, p < 0.01), and the early osteogenic activity of LPS + MФ+HA-DA/Alg-PBA/TA@Ag NPs hydrogel group was enhanced by 56.74 times compared with that of the LPS + MФ group.

Based on the biomarker values related to serum L-fucose levels in this study, a significant trend (P < 0.01) was observed with the progression of OSMF (C) ( Table 2 ).

Comparison of the distribution of SCAI SHOCK stages revealed a significant trend towards a higher proportion of stages D (64.7% vs. 25.0%, P < 0.01) among the 1‐year non‐survivors.

[ 63 ], conducted a case-control study in the USA and found a significant trend for increased breast cancer risk in post-menopausal women exposed to high PAH levels at birth ( P = 0.01), with ORs ranging from 1.94 to 2.42, suggesting a dose-response relationship.

Repeated measure ANOVA analysis showed a significant trend in total cholesterol, triglycerides, and VLDL-C decrease in GCP ( p < 0.01), but the trend in LDL-C decrease was not significant ( Table 3 ).