“a significant trend”

Gestational week at examination, LDL-C, HDL-C, and GWG showed a significant trend of first increasing and then decreasing with the TyG index ( P < 0.01).

Based on the biomarker values related to serum L-fucose levels in this study, a significant trend (P < 0.01) was observed with the progression of OSMF (C) ( Table 2 ).

However, a significant trend of higher LN count and higher likelihood of liver metastases was observed ( P = 0.010).

Repeated measure ANOVA analysis showed a significant trend in total cholesterol, triglycerides, and VLDL-C decrease in GCP ( p < 0.01), but the trend in LDL-C decrease was not significant ( Table 3 ).

If a significant trend was detected at p ≤ 0.01, Williams’ test was used [ 21 ]; if the trend was not significant Dunnett’s test was used [ 22 ].

Plasma NGAL levels also increased progressively with AKI stage: 481.6 ng/mL (stage 1), 625.5 ng/mL (stage 2), and 760.2 ng/mL (stage 3), showing a significant trend ( P < 0.01).

Comparison of the distribution of SCAI Shock stages revealed a significant trend towards a higher proportion of stages D (58.9% vs. 47.2%) and E (1.8% vs. 0.4%) ( P = 0.01) among the 1‐year non‐survivors.

Similarly, there was a significant trend in all item scores (with the exception of environmental autonomy) across the cognitive subgroups (all p<0.01).

Compared with the latter, our cohort presented increased mutation frequency of DUSP2 , BTG2 , IRF4 , MEF2B , MYC , CD79B , BCL7A , NFKBIE , FAS , and CIITA ( p < 0.05), with a significant trend toward changes in TP53 , CCND3 , CD58 , and CXCR4 ( p < 0.01).

However, among kidney transplant patients younger than 50 years at the time of transplantation ( n = 754), there was a significant trend for increasing the occurrence of post-transplant CV complications along the consecutive KDRI quartiles (χ 2 = 7.3; p < 0.01), with the frequency of CVEs across the study groups as follows: Q1 13/205, Q2 23/179, Q3 24/166, and Q4 21/123.

Regression analysis indicated a significant trend ( P =.01) increase in app release, with a 2.40 unit increase per year before 2020 and a 7.01 unit decrease after, showing a post-2020 decline of 4.61 units per year.

There was also a significant trend ( p < 0.01) in prevalence of lower respiratory symptoms that improved when away from the building: 52% of those with postoccupancy-onset asthma, 41% of those with adult preoccupancy-onset asthma, 27% of those with childhood asthma, and 23% of those with no physician-diagnosed asthma ( Table 4 ).

In terms of lung cancer, sensitivity analysis using adjusted estimates only showed a significant trend towards a higher incidence of lung cancer among HF patients [HR, 1.68 (95% CI: 1.13–2.49), P = 0.01] (see Supplementary material online , Figure S9 ).

The SNAF group showed a significant trend toward wild-type p53 and p16 positivity ( p < 0.01).

Compared to controls, S-losers had significantly lower plasma anti-HBc levels prior to HBsAg seroclearance, with a significant trend of declining plasma anti-HBc 8–5 years prior to HBsAg seroclearance (p < 0.01), while such trend was not observed in controls.

At the seasonal level, we found a significant trend in NEE only in autumn, which indicated that the forest's net C sink increased during autumn over the 26 years of the study ( p < 0.01; Table 1 ). 3.2 Trends in Daily NEE Fluxes Over Time To assess the effects of climate change on NEE throughout the study period, we analyzed the days with the strongest net C uptake, that is, 1st, 5th percentiles of NEE c,DOY , and strongest net C loss, that is, 95th and 99th percentiles of NEE c,DOY , as well as the median NEE c,DOY during the 26‐year period (Figure S4 ).

In the treatment-group, there was a significant trend of lower levels of proinflammatory cytokine interleukin (IL)-2 during 6-hour adsorption compared to the control group ( P = .01).

Experimental mice on HFD exhibited a significant trend of weight gain compared with WT mice fed on ND and HFD ( p < 0.01, ApoE −/− /HFD vs.

However, a significant trend was noted where the proportion of individuals with high LDL-PRS increased with rising LDL-indicating a polygenic component at play ( p = 0.01) (Supplementary Fig. 2).

2 a ) further supported a significant trend toward higher ω values (indicative of relaxation of selection) in lungfish (Mann–Whitney U test, P < 0.01).

The current study results consistently demonstrated a significant trend ( P < 0.01).

The fully adjusted model demonstrated a significant trend correlating increased TTHC (P<0.01 for trend), SR (P<0.001 for trend), and Ki-67 expression (P=0.004 for trend) with ALNM.

There was also a significant trend of the protective effect of NHSL1 rs4896367 on IA, but at a nominal level ( P = 0.0110, Supplementary Table 3 ).

A significant trend was observed in the subscale Enjoyment of Food and Emotional Overeating in children with obesity ( p = 0.011 and p = 0.008), abdominal obesity ( p = 0.031 and p = 0.017), and cardiometabolic risk ( p = 0.036 and p = 0.049) in the non-EBF group, compared to those who were EBF up to 6 months of age.

Binary logistic regression analysis showed a significant trend of association between TNK treatment and lower END risk [odds ratio (OR) = 0.069, 95% confidence interval (CI): 0.009–0.545, p = 0.011].