“a significant trend”

Compared to controls, S-losers had significantly lower plasma anti-HBc levels prior to HBsAg seroclearance, with a significant trend of declining plasma anti-HBc 8–5 years prior to HBsAg seroclearance (p < 0.01), while such trend was not observed in controls.

Experimental mice on HFD exhibited a significant trend of weight gain compared with WT mice fed on ND and HFD ( p < 0.01, ApoE −/− /HFD vs.

Survival On survival analysis, there was a significant trend of the worst OS of advanced-stage patients based on FIGO 2009 ( P = 0.011 ) ( Figure 2A ) and FIGO 2018 staging ( P = 0.02 ) ( Figure 2B ), respectively.

We next compared the frequency of TOX expressing T EM cells over time and observed a significant trend toward increasing cell frequency among patients with non-sustained MRD negativity and prior HDM-ASCT (Wilcoxon rank-sum test P = 0.011, Fig. 3b ).

A significant trend was observed in the subscale Enjoyment of Food and Emotional Overeating in children with obesity ( p = 0.011 and p = 0.008), abdominal obesity ( p = 0.031 and p = 0.017), and cardiometabolic risk ( p = 0.036 and p = 0.049) in the non-EBF group, compared to those who were EBF up to 6 months of age.

There was also a significant trend of the protective effect of NHSL1 rs4896367 on IA, but at a nominal level ( P = 0.0110, Supplementary Table 3 ).

Binary logistic regression analysis showed a significant trend of association between TNK treatment and lower END risk [odds ratio (OR) = 0.069, 95% confidence interval (CI): 0.009–0.545, p = 0.011].

Moreover, we observed a significant trend towards a decline in urine phosphate excretion, visible as early as the third month of treatment (0.53 ± 0.18 vs. 0.44 ± 0.17 g/24 h; p = 0.011).

The relationship between FS and FNPA was explored, and a significant trend was noted with FNPA scores in this population; however, a limited range of FS scores may have affected this finding ( β = 0.534, CI 0.126, 0.941; p = .011).

In contrast, antidiabetic therapy demonstrated a significant trend across SI quartiles ( P = 0.011).

The log rank analyses ( Figures 1 and 2 ) showed that the RFS and OS were significantly different among the quartiles with a significant trend towards worse survival in more deprived quartiles ( p = 0.012, and 0.011, respectively).

Results: After adjusting for covariates, a significant trend was found between the dietary iron and elevated fasting glucose ( p = 0.012), whereas no such trend was observed for the rs864745 ( p = 0.932).

After adjusting for age, sex, smoking status, and use of lipid-lowering and antihypertensive medications, we determined that participants carrying the minor alleles of the rs117685211 genotype exhibited a significant trend of higher levels of Ox-HDL in the additive and dominant models ( p = 0.012 and 0.002, respectively), and conversely showed a significant trend of lower levels of ApoA1 and HDL-P (including L, M, and S-HDL-P; all p values were ≤0.001 in the additive and dominant models).

Similarly, a significant trend was also found between mean age and blood loss in the NE (Omnibus p = 0.012) and CR (Omnibus p = 0.04) groups (Supplementary Figure S21‐22 ). 5 Discussion NE evacuation was initially suggested by Auer et al. and has since developed into a potentially effective surgical technique for managing spontaneous supratentorial ICH due to its high evacuation rate, superior protection of the surrounding brain tissue, and lower complication rates (Ye et al. 2017 ; Zhang et al. 2014 ).

Importantly, there was a significant trend indicating that as D-dimer levels rose, the risk of mortality also increased ( p for trend, HR 1.15, 95% CI = 1.03 ~ 1.28, p = 0.012).

Critically, the fundamental linear dose-response relationship was reaffirmed by a significant trend across quartiles (p = 0.013) and a consistently positive continuous association in both the primary (HR 1.38 per SD) and sensitivity (HR 1.65 per SD) models.

In addition, there was a significant trend for the spatial variability of TTP to increase with age ( R = 0.34, 0.011/year, p = 0.013).

The distribution of risk categories at initial presentation showed a significant trend towards higher risk in extragonadal GCTs (p=0.013).

There was a significant trend toward increased use of systemic HRT (73.8 % vs. 100 %, p = 0.013), including transdermal HRT (45.2 % vs. 84.2 %, p = 0.004) in the weight gain cohort.

Moreover, linear-by-linear association analysis demonstrated a significant trend ( p = 0.013), indicating that higher tumor grade was associated with an increased risk of death within two years. 4.

We also discovered a significant trend of shortened survival in patients of Cluster B (HR = 2.132, 95%CI: 1.014–4.484; Renyi test p = 0.013, see Figure 1 G).

At the same time, a significant trend in ESR level increase with CAS gradation increase was registered in men ( P = 0.013), which was not registered in women ( P = 0.66).

When TyG index was assessed as quartiles, compared with the reference group (Quartile 1), the hazard ratio of stroke was 1.04 in Quartile 2, 1.43 in Quartile 3, and 1.45 in Quartile 4, with a significant trend test ( P = 0.013).

However, there was a significant trend in the increase of PV velocity within 12 postoperative months in the control group compared with the valsartan group ( P =0.014; Figure 4A ).

After adjusting for all factors, the ORs for NHHR tertiles 2 and 3 were 0.76 (95% CI: 0.58–0.99) and 0.70 (95% CI: 0.53–0.94), respectively, with a significant trend ( p = 0.014).