Finally, stride time variability showed a significant trend ( p = 0.033) in both bilateral KOA patients ( r = 0.401, p < 0.001) and healthy controls ( R = 0.672, p < 0.001).
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The corresponding comparisons to peak leukocyte counts are not shown, yielding a significant trend ( p = 0.033) with native T 1 .
Longitudinal analyses revealed a significant trend of lower PRL concentrations with increasing number of MetS components in women (p = 0.033), but not in men (p = 0.331) (Figure 1 ).
By time-to-event analysis ( Figure 2 ), there was a significant trend toward improved VE ( P = 0.033, logrank test for trend) from saline controls to PfSPZ Vaccine to PfSPZ-CVac.
Subgroup analysis (tracer type, molecular subtype) was corrected using Bonferroni, and the corrected P -value threshold was 0.05/2 = 0.025: The original P = 0.037 in the tracer group → adjusted P = 0.074 (with a significant trend), and the original P = 0.033 in the molecular subtype → adjusted P = 0.066 (the differential trend still exists).
There was a significant trend towards more severe pruritus among poor responders compared with good responders ( p = 0.033), with a higher proportion of poor responders reporting moderate to severe symptoms.
Secondary Outcome CRP reduction among the inflammatory markers showed a significant trend in the tocilizumab group by day 3 ( p = 0.033) ( Table 4 and Fig. 2 ).
At day 3 a significant trend of increased expression was observed for COL2A1 ( p = 0.034) and COL10A1 ( p = 0.012) with wildtype GDF5, and for COL2A1 ( p = 0.0068), MMP1 ( p = 0.037) and COL10A1 ( p = 0.027) with GDF5 variant.
A significant trend towards decreased survival in patients with alcohol history compared to the patients without alcohol history, 42.3% vs. 76.9% (p=0.034), and a decreased survival rates in p16 negative patients compared to p16 positive patients, 43% vs. 69.7% (p=0.034) was noticed.
Using water Mn concentrations as a continuous variable, the adjusted OR was 0.75 (95% CI 0.58–0.98, model I) per 1 mg/L (1,000 μg/L) increase in Mn concentration, with a significant trend ( P =0.034).
When ANC maximum was measured, there was a significant trend ( P = 0.034) for the maximum ANC level achieved in stage II during cycle 1.
Separate trend analyses showed a significant trend in the non-obese group (χ 2 1 =4.520, P=.034) and no significance in the obese (χ 2 1 =0.679, P=.410).
The OR for the highest vs the lowest quintile of GI was 2.1 (95% CI: 1.2–3.6), with a significant trend in risk ( P =0.034).
When investigating the interaction between allocation and time, only actigraphy-measured sleep efficiency showed a significant trend over time ( p =.034).
As demonstrated by linear regression model in Table 4 we observed a significant trend that survivors with CCI ≥ 1 ( β = 5.2, p = 0.034), tumor sits at nasopharynx ( β =-9.1, p = 0.034), or treated by 2DRT ( β =-12.2, p < 0.01) had a higher probability to report a high level of xerostomia.
For TTP as well as OS, there was a significant trend for increased survival in relation to increased expression of MHC II by the tumour ( P =0.034 and 0.043, respectively; log rank test for trend).
The multivariant adjusted model in NHANES found a significant trend ( P = 0.034) in increased risk for developing breast cancer across the four quartiles of urinary cadmium ( 52 ).
Overall survival differed significantly by tumor type (p = 0.0395), with a significant trend across groups (p = 0.0340).
A significant trend towards better local control in hypoFx patients could be observed (overall LC 58.2% for nFx vs 90.5% for hypoFx, HR = 0.15, 95%CI: 0.02-0.86, p = 0.034) and high-dose PTV volume > 60 cm3 was a significant risk factor for locoregional progression (Figure 1). 11 patients (28.9%) developed ≥ G3 serious late complications, mostly soft tissue necrosis and infections which eventually improved in 6 of them.
Also, there was a significant trend towards less advanced nodal disease in the neoadjuvant group than in the adjuvant group ( P = 0.034) ( Table 3 ). 3.5.
A significant trend indicating increased Nef-mediated SERINC5 downregulation function correlated with higher viral load was observed in subtype B viruses ( r = 0.6685 and P = 0.0346, Fig. 2 e).
There was a significant trend with average hours of night work per week ( P = 0.035), but no significantly raised risks for hours worked per night, nights worked per week, average hours worked per week, cumulative years of employment, cumulative hours, time since cessation, type of occupation, age starting night shift work, or age starting in relation to first pregnancy.
There was a significant trend of TBUT improvement over the 12 weeks ( P =0.035) with no significant difference between treatment groups ( P =0.88).
Moreover, a significant trend towards increased in-hospital mortality was found in propensity score-adjusted regression in the unmatched population (odds ratio 3.12, p = 0.035), but this result was not significant in the matched cohort ( p = 0.095). 4.
When analyzed as a categorical variable, the multivariable- AOR from the lowest to highest quintiles of percentage energy from carbohydrate were 1 (reference), 1.062 (95% CI: 0.892–1.264), 1.263 (95% CI: 1.031–1.546), and 1.411 (95% CI: 1.083–1.839), with a significant trend ( P = 0.035).