“a suggestive trend”

Neither M1-type nor M2-type gene expression signatures were significantly enhanced in these mice, though there was a suggestive trend in the M2 signature (Fig. 2d, e ; P = 0.32 for M2).

In this same study, there was a suggestive trend (p value equal to 0.056) between fasting glucose and cardiovascular events.

Results Among girls, we observed a suggestive trend of increased odds of breast and pubic hair development with higher Alu and LINE-1 methylation in 9-year-old blood, respectively.

Additional comorbidities, including COPD and hypertension, were identified as possible risk factors, while CKD showed only a suggestive trend and did not achieve statistical significance.

Although the ANOVA comparing NfL changes among ATN groups revealed only a suggestive trend towards significance (likely due to the limited sample size), post hoc analysis demonstrated that the rate of increase was more pronounced in patients with ATN+ status compared to those with isolated A+.

In adjusted models, a suggestive trend across tertiles was observed for IL‐1β (trend p ‐value 0.01).

However there was a suggestive trend, although not significant, that the longer it took to get to hospital and hence more fare paid, the more likely it was a participant to utilize PMTCT services for the first time in CPGH ( Table 2 ).

Here, we uncovered a striking signature of selection at β A 21 in Ancash, and a suggestive trend in Lima.

In both the continuous and categorical eGDR subgroup analyses, although the interaction with diabetes status was not statistically significant, we observed a suggestive trend indicating that eGDR may have a stronger predictive effect on WMH volume in non-diabetic individuals than in those with diabetes. 3.4 Sensitivity analyses Multiple sensitivity analyses consistently supported the robustness of our findings.

Although no significant interactions were observed for any of the subgroups, a suggestive trend was noted between ventilated and non-ventilated patients with the combination therapy appeared to be more beneficial in ventilated patients.

When looking at continuous differences in HDI, we observed a suggestive trend in the effect especially for congenital abnormalities, preterm birth and SGA ( Supplementary Figure S4 ).

Specifically, among African Americans, there was a suggestive trend where ω-3 supplementation seemed to lower the risk of adenomas, hinting at a connection between ω-3 fatty acids and immune system adjustments.

In our analyses, we found a suggestive trend for weaker TL–mortality risk associations in reptiles compared to birds that may have been driven by a single outlying study.

Although we did not see any association between sun exposure and St Jude staging, there was a suggestive trend in the ISS staging, a staging system that better captures current understanding of disease spread and risk of extraocular involvement.

and Aslanides et al ., which concluded that LASIK Xtra eyes showed no significant hyperopic regression but LASIK-only eyes showed a suggestive trend towards hyperopic regression.[ 72 , 73 ] With PRK Xtra as well, Lee et al . observed similar keratometric changes in both PRK Xtra and PRK-only groups over 1-year follow-up.

For all-cause mortality, there was a clear trend towards larger proportional effects at younger ages and a suggestive trend of larger proportional effects in those with a higher proportion of Indigenous American ancestry.

However, while absolute rates of vaccination preintervention and postintervention remained low, we demonstrated a 10-fold improvement in hepatitis A vaccination from the preintervention group (2.2%) to the postintervention group (21.7%; OR 12.5 (1.5, 102.3)), as well as a suggestive trend towards increased awareness by treating physicians.

89 Metabolomic profiling only revealed a suggestive trend of fecal L-Fucose in Atg16l1 ∆IEC mice at trimester 3, which may warrant further investigation due to the important role of fucosylation as a post-translational protein modification in Crohn’s disease and colorectal cancer. 26 , 90–92 We found consistent evidence for an increase in chitin-degradation in Atg16l1 ∆IEC pregnant mice in trimester 3 (day 18 after timed mating), both by higher abundance of the pathway in metagenomic data, as well as increased levels of its metabolite N-acetylglucosamine in the feces of these mice.

Although no significant association was found between this SNP and the overall risk of AIT, a suggestive trend was observed between rs1126797 genotypes and thyroid volume in affected individuals.

For dysmenorrhea and EC, the weighted median method produced p values ranging from 0.032 to 0.086, which aligned with the IVW results and indicated a suggestive trend ( Table 1 ).

Finally, while we did not find a statistically significant interaction between SAN and SN connectivity to predict emotion identification, it showed a suggestive trend, indicating the interaction between the two networks may be meaningfully related to emotion reading in a larger sample.

When these findings are considered alongside results from the multi-ethnic STAR*D cohort, also including participants with MDD, in which no significant associations were observed in Caucasian or African American participants, but a suggestive trend was present in Latinos ( 37 ), the overall pattern is consistent with a population-specific modulation of antidepressant response rather than a universal pharmacogenetic effect.

We found no clearly significant effects of Vitamin B12 supplementation on the outcome measures, although there was a suggestive trend towards reduced anxiety, and a trend towards an increase in visual contrast thresholds.

Contrary to the predictions of the problem individuals hypothesis, we did not find a reduction, but instead a suggestive trend of an increase, in conflict kills following periods with high conflict removal of bears.

L + ZOL: 9.0%) but a suggestive trend probably due to extremely low number of events.